Pharmacological Polarization of Tumor‐Associated Macrophages Toward a CXCL9 Antitumor Phenotype

Pharmacological Polarization of Tumor‐Associated Macrophages Toward a CXCL9 Antitumor Phenotype

Abstract Tumor‐associated macrophages (TAM) are a diverse population of myeloid cells that are often abundant and immunosuppressive in human cancers. CXCL9Hi TAM has recently been described to have an antitumor phenotype and is linked to immune checkpoint response. Despite the emerging understanding...

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Bibliographic Details
Main Authors: Noah Enbergs, Elias A. Halabi, Anne‐Gaëlle Goubet, Kelton Schleyer, Ina R. Fredrich, Rainer H. Kohler, Christopher S. Garris, Mikaël J. Pittet, Ralph Weissleder
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
CXCL9
IFNg
macrophage
nanoparticles
PARP7
polarization
Online Access:https://doi.org/10.1002/advs.202309026

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