Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells

Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells

Sirtuin 6 (SIRT6) is a member of the mammalian NAD<sup>+</sup>-dependent deac(et)ylase sirtuin family. SIRT6’s anti-inflammatory roles are emerging increasingly often in different diseases and cell types, including endothelial cells. In this study, the role of SIRT6 in pro-inflammatory c...

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Bibliographic Details
Main Authors: Cecilia Astigiano, Francesco Piacente, Maria Elena Laugieri, Andrea Benzi, Christian A. Di Buduo, Carolina P. Miguel, Debora Soncini, Michele Cea, Antonella Antonelli, Mauro Magnani, Alessandra Balduini, Antonio De Flora, Santina Bruzzone
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
SIRT6
ATP
NAD<sup>+</sup>
inflammation
endothelium
purinergic receptors
Online Access:https://www.mdpi.com/1422-0067/24/7/6759

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