On-line Urea Monitoring during Hemodialysis: A Review
In recent years, methods of on-line urea <i> concentration </i> and on-line urea <i> clearance </i> monitoring have been proposed for control of dialysis dose (Kt/V) and protein catabolic rate (PCR) in patients on regular dialysis therapy; these offer an alternative to the es...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2001-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Subjects: | |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=3;spage=364;epage=374;aulast=Stiller |
| _version_ | 1828311955684720640 |
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| author | Stiller S Al-Bashir A Mann Helmut |
| author_facet | Stiller S Al-Bashir A Mann Helmut |
| author_sort | Stiller S |
| collection | DOAJ |
| description | In recent years, methods of on-line urea <i> concentration </i> and on-line urea <i> clearance </i> monitoring have been proposed for control of dialysis dose (Kt/V) and protein catabolic rate (PCR) in patients on regular dialysis therapy; these offer an alternative to the established methods of urea kinetics based on pre- and post-dialysis measurements of urea concentration. In contrast to such conventional urea kinetics, the new methods deliver results in real time and treatment parameters can be changed instantly. Three on-line measurement methods are to be distinguished: monitoring of urea <i> concentration </i> in <i> ultrafiltrate, </i> monitoring of urea <i> concentration </i> in dialysate (both yield Kt/V and PCR), and monitoring of urea <i> clearance </i> based on conductivity measurements. Some of these approaches are already applied commercially. Here, these methods are compared using results obtained from laboratory and clinical studies. The on-line methods are found to be more accurate than methods based on pre- and post-dialysis urea concentrations, and to be better suited for clinical routine. This paper outlines the principal methods, reviews the present literature, gives an overview of the applications and compares them to conventional pre- and post-dialysis concentration-based methods of urea kinetics. It is concluded that these methods are likely to find a widespread application in the control of dialysis adequacy. |
| first_indexed | 2024-04-13T16:08:11Z |
| format | Article |
| id | doaj.art-9aee9a423101483388eb384a1e4b1e2e |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-04-13T16:08:11Z |
| publishDate | 2001-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-9aee9a423101483388eb384a1e4b1e2e2022-12-22T02:40:20ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422001-01-01123364374On-line Urea Monitoring during Hemodialysis: A ReviewStiller SAl-Bashir AMann HelmutIn recent years, methods of on-line urea <i> concentration </i> and on-line urea <i> clearance </i> monitoring have been proposed for control of dialysis dose (Kt/V) and protein catabolic rate (PCR) in patients on regular dialysis therapy; these offer an alternative to the established methods of urea kinetics based on pre- and post-dialysis measurements of urea concentration. In contrast to such conventional urea kinetics, the new methods deliver results in real time and treatment parameters can be changed instantly. Three on-line measurement methods are to be distinguished: monitoring of urea <i> concentration </i> in <i> ultrafiltrate, </i> monitoring of urea <i> concentration </i> in dialysate (both yield Kt/V and PCR), and monitoring of urea <i> clearance </i> based on conductivity measurements. Some of these approaches are already applied commercially. Here, these methods are compared using results obtained from laboratory and clinical studies. The on-line methods are found to be more accurate than methods based on pre- and post-dialysis urea concentrations, and to be better suited for clinical routine. This paper outlines the principal methods, reviews the present literature, gives an overview of the applications and compares them to conventional pre- and post-dialysis concentration-based methods of urea kinetics. It is concluded that these methods are likely to find a widespread application in the control of dialysis adequacy.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=3;spage=364;epage=374;aulast=StillerHemodialysisUrea clearanceQuality controlUrea kinetics. |
| spellingShingle | Stiller S Al-Bashir A Mann Helmut On-line Urea Monitoring during Hemodialysis: A Review Saudi Journal of Kidney Diseases and Transplantation Hemodialysis Urea clearance Quality control Urea kinetics. |
| title | On-line Urea Monitoring during Hemodialysis: A Review |
| title_full | On-line Urea Monitoring during Hemodialysis: A Review |
| title_fullStr | On-line Urea Monitoring during Hemodialysis: A Review |
| title_full_unstemmed | On-line Urea Monitoring during Hemodialysis: A Review |
| title_short | On-line Urea Monitoring during Hemodialysis: A Review |
| title_sort | on line urea monitoring during hemodialysis a review |
| topic | Hemodialysis Urea clearance Quality control Urea kinetics. |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2001;volume=12;issue=3;spage=364;epage=374;aulast=Stiller |
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