Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran
Background: Ganoderma lucidum belongs to Ganodermataceae family and is a famous medicinal fungus with medicinal properties like antidiabetic, antihypertension, immunomodulating, antiviral and antibacterial effects. Objective: Due to its great medicinal effect and lack of investigation on Iranian spe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Institue of Medicinal Plants, ACECR
2009-12-01
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| Series: | Journal of Medicinal Plants |
| Subjects: | |
| Online Access: | http://jmp.ir/article-1-348-en.html |
| _version_ | 1818602102653452288 |
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| author | S Keypour Sangesari H Riahi H Rafati M.F Moradali |
| author_facet | S Keypour Sangesari H Riahi H Rafati M.F Moradali |
| author_sort | S Keypour Sangesari |
| collection | DOAJ |
| description | Background: Ganoderma lucidum belongs to Ganodermataceae family and is a famous medicinal fungus with medicinal properties like antidiabetic, antihypertension, immunomodulating, antiviral and antibacterial effects. Objective: Due to its great medicinal effect and lack of investigation on Iranian species, this study was performed. Methods: In this study, we have investigated antibacterial activity of aqueous extract at four concentrations (50, 125, 250, 500 mg ml-1) against 3 standard Gram positive bacteria (Bacillus subtilis, Staphylococcus aureus, Entrococcus fecalis) and 2 standard Gram negative bacteria (Pseudomonas aeroginosa and Escherichia coli) by using Disk diffusion method. Total polysaccharide of the aqueous extract and sugar composition were analyzed by phenol sulfuric acid method and GC/MS, respectively. Results: The results indicated that the aqueous extract had antibacterial effect against Pseudomonas aeroginosa at concentration of 500 mg ml-1. The polysaccharide content was 37.751 mg g-1 and the monosaccharide’s constituents were identified. Conclusion: Based on this finding the fungus contains a great amount of polysaccharides that can be use for medicinal properties, but it is not recommended for antibacterial usage according to its weak inhibitory activity. |
| first_indexed | 2024-12-16T13:01:57Z |
| format | Article |
| id | doaj.art-9aef123fa8504aa2be2765598b5248f7 |
| institution | Directory Open Access Journal |
| issn | 2717-204X 2717-2058 |
| language | English |
| last_indexed | 2024-12-16T13:01:57Z |
| publishDate | 2009-12-01 |
| publisher | Institue of Medicinal Plants, ACECR |
| record_format | Article |
| series | Journal of Medicinal Plants |
| spelling | doaj.art-9aef123fa8504aa2be2765598b5248f72022-12-21T22:30:48ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582009-12-018325359Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from IranS Keypour Sangesari0H Riahi1H Rafati2M.F Moradali3 1- Plant systematic, Bioscience Faculty, Shahid Beheshti University, Evin 2- Plant biology Department, Bioscience Faculty, Shahid Beheshti University, Evin, Tehran 3- Phytochemistry Department, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin 4- Microbial Biotechnology and Biosafety Department, Agricultural Biotechnology Research Institute of Iran Background: Ganoderma lucidum belongs to Ganodermataceae family and is a famous medicinal fungus with medicinal properties like antidiabetic, antihypertension, immunomodulating, antiviral and antibacterial effects. Objective: Due to its great medicinal effect and lack of investigation on Iranian species, this study was performed. Methods: In this study, we have investigated antibacterial activity of aqueous extract at four concentrations (50, 125, 250, 500 mg ml-1) against 3 standard Gram positive bacteria (Bacillus subtilis, Staphylococcus aureus, Entrococcus fecalis) and 2 standard Gram negative bacteria (Pseudomonas aeroginosa and Escherichia coli) by using Disk diffusion method. Total polysaccharide of the aqueous extract and sugar composition were analyzed by phenol sulfuric acid method and GC/MS, respectively. Results: The results indicated that the aqueous extract had antibacterial effect against Pseudomonas aeroginosa at concentration of 500 mg ml-1. The polysaccharide content was 37.751 mg g-1 and the monosaccharide’s constituents were identified. Conclusion: Based on this finding the fungus contains a great amount of polysaccharides that can be use for medicinal properties, but it is not recommended for antibacterial usage according to its weak inhibitory activity.http://jmp.ir/article-1-348-en.htmlganoderma lucidumantibacterial activityphenol sulfuric acidtotal polysaccharide |
| spellingShingle | S Keypour Sangesari H Riahi H Rafati M.F Moradali Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran Journal of Medicinal Plants ganoderma lucidum antibacterial activity phenol sulfuric acid total polysaccharide |
| title | Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran |
| title_full | Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran |
| title_fullStr | Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran |
| title_full_unstemmed | Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran |
| title_short | Antibacterial Activity of Aqueous Extract of Ganoderma lucidum Karst. (Basidiomycota) from Iran |
| title_sort | antibacterial activity of aqueous extract of ganoderma lucidum karst basidiomycota from iran |
| topic | ganoderma lucidum antibacterial activity phenol sulfuric acid total polysaccharide |
| url | http://jmp.ir/article-1-348-en.html |
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