Comparison of Global DNA Methylation Patterns in Human Melanoma Tissues and Their Derivative Cell Lines

DNA methylation is a heritable epigenetic mark that is fundamental to mammalian development. Aberrant DNA methylation is an epigenetic hallmark of cancer cells. Cell lines are a critical in vitro model and very widely used to unravel mechanisms of cancer cell biology. However, limited data are avail...

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Bibliographic Details
Main Authors: Euan J. Rodger, Suzan N. Almomani, Jackie L. Ludgate, Peter A. Stockwell, Bruce C. Baguley, Michael R. Eccles, Aniruddha Chatterjee
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/9/2123