Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature
Adult onset Still’s disease (AOSD) is a systemic inflammatory disease with exact etiology and pathogenesis yet to be discovered. AOSD, being an important cause of fever of unknown origin, is diagnosed after ruling out infections, malignancy and other rheumatologic diseases. It may present with fever...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2017-05-01
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| Series: | Italian Journal of Medicine |
| Subjects: | |
| Online Access: | http://www.italjmed.org/index.php/ijm/article/view/824 |
| _version_ | 1797424774529417216 |
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| author | Harpreet Singh Deepak Jain Saroj Dhankhar Rekha Mathur |
| author_facet | Harpreet Singh Deepak Jain Saroj Dhankhar Rekha Mathur |
| author_sort | Harpreet Singh |
| collection | DOAJ |
| description | Adult onset Still’s disease (AOSD) is a systemic inflammatory disease with exact etiology and pathogenesis yet to be discovered. AOSD, being an important cause of fever of unknown origin, is diagnosed after ruling out infections, malignancy and other rheumatologic diseases. It may present with fever without typical rash although typical triad is of fever, joint pain and rash. A 35-year-old previously healthy man was referred to our hospital with 6 months of fever, joint pain and weight loss. Examination and investigations revealed anemia, leukocytosis (predominant neutrophilia), lymphadenopathy, hepatomegaly, arthritis and evidence of interstitial lung disease with raised serum ferritin levels. Hematological disorders, infections and other rheumatologic diseases were excluded. The diagnosis of adult onset Still’s disease can be very difficult as there are no specific tests and diagnosis is based on symptom complex. AOSD presenting as fever of unknown origin could be a challenge for the physician to diagnose and manage timely. |
| first_indexed | 2024-03-09T08:06:43Z |
| format | Article |
| id | doaj.art-9aef785e90e74fb2b922306e0d751884 |
| institution | Directory Open Access Journal |
| issn | 1877-9344 1877-9352 |
| language | English |
| last_indexed | 2024-03-09T08:06:43Z |
| publishDate | 2017-05-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Italian Journal of Medicine |
| spelling | doaj.art-9aef785e90e74fb2b922306e0d7518842023-12-02T23:57:34ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522017-05-0111438839210.4081/itjm.2017.824618Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literatureHarpreet Singh0Deepak Jain1Saroj Dhankhar2Rekha Mathur3Department of Medicine and Division of Rheumatology, Pt. B.D. Sharma University of Health Sciences, RohtakDepartment of Medicine and Division of Rheumatology, Pt. B.D. Sharma University of Health Sciences, RohtakDepartment of Medicine and Division of Rheumatology, Pt. B.D. Sharma University of Health Sciences, RohtakDepartment of Medicine and Division of Rheumatology, Pt. B.D. Sharma University of Health Sciences, RohtakAdult onset Still’s disease (AOSD) is a systemic inflammatory disease with exact etiology and pathogenesis yet to be discovered. AOSD, being an important cause of fever of unknown origin, is diagnosed after ruling out infections, malignancy and other rheumatologic diseases. It may present with fever without typical rash although typical triad is of fever, joint pain and rash. A 35-year-old previously healthy man was referred to our hospital with 6 months of fever, joint pain and weight loss. Examination and investigations revealed anemia, leukocytosis (predominant neutrophilia), lymphadenopathy, hepatomegaly, arthritis and evidence of interstitial lung disease with raised serum ferritin levels. Hematological disorders, infections and other rheumatologic diseases were excluded. The diagnosis of adult onset Still’s disease can be very difficult as there are no specific tests and diagnosis is based on symptom complex. AOSD presenting as fever of unknown origin could be a challenge for the physician to diagnose and manage timely.http://www.italjmed.org/index.php/ijm/article/view/824Adult onset still’s diseasefever of unknown originarthritisleukocytosis. |
| spellingShingle | Harpreet Singh Deepak Jain Saroj Dhankhar Rekha Mathur Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature Italian Journal of Medicine Adult onset still’s disease fever of unknown origin arthritis leukocytosis. |
| title | Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature |
| title_full | Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature |
| title_fullStr | Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature |
| title_full_unstemmed | Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature |
| title_short | Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature |
| title_sort | adult onset still s disease presenting as fever of unknown origin a case report with review of literature |
| topic | Adult onset still’s disease fever of unknown origin arthritis leukocytosis. |
| url | http://www.italjmed.org/index.php/ijm/article/view/824 |
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