The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation
Cryopreservation is a technique that offers various advantages, especially in fish, among others, that makes the reproduction of species easier through a constant supply of sperm, synchronization of the gamete availability of both sexes, storage of semen for genetic improvement programs, reduction i...
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MDPI AG
2022-03-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/6/791 |
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| author | Alexandra I. Alevra Athanasios Exadactylos Eleni Mente Serafeim Papadopoulos |
| author_facet | Alexandra I. Alevra Athanasios Exadactylos Eleni Mente Serafeim Papadopoulos |
| author_sort | Alexandra I. Alevra |
| collection | DOAJ |
| description | Cryopreservation is a technique that offers various advantages, especially in fish, among others, that makes the reproduction of species easier through a constant supply of sperm, synchronization of the gamete availability of both sexes, storage of semen for genetic improvement programs, reduction in the cost by eliminating the need to maintain male broodstock, and conserving the gametes of endangered species. However, freezing and warming procedures for cryopreservation lead to a reduction in the quality and viability of cryopreserved sperm because of oxidative stress. For this reason, the enrichment of extender media with antioxidants is a common method of cryopreservation of the semen of several fish species. Recently, many studies have been published for the protective role of antioxidants and especially of melatonin on male fertility preservation both in farm animals and humans, demonstrating the beneficial effects of melatonin as a sperm cryoprotectant. On the other hand, very few studies were conducted using melatonin as an antioxidant in different male fish species for semen cryopreservation. We conclude that the use of moderate concentrations of melatonin are beneficial to semen preservation, and the mechanisms through which melatonin acts positively on spermatozoa need to be further investigated to establish improvement protocols for cryopreservation in fish species. |
| first_indexed | 2024-03-09T20:12:47Z |
| format | Article |
| id | doaj.art-9af037d3e73c48bb89eb0027c72c733d |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T20:12:47Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-9af037d3e73c48bb89eb0027c72c733d2023-11-24T00:10:11ZengMDPI AGAnimals2076-26152022-03-0112679110.3390/ani12060791The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish CryopreservationAlexandra I. Alevra0Athanasios Exadactylos1Eleni Mente2Serafeim Papadopoulos3Hydrobiology-Ichthyology Laboratory, Department of Ichthyology and Aquatic Environment, University of Thessaly, Fytokou Str., 38446 Volos, GreeceHydrobiology-Ichthyology Laboratory, Department of Ichthyology and Aquatic Environment, University of Thessaly, Fytokou Str., 38446 Volos, GreeceLaboratory of Ichthyology-Culture and Pathology of Aquatic Animals, School of Veterinary Medicine, Aristotle University of Thessaloniki, University Campus, 54006 Thessaloniki, GreeceHydrobiology-Ichthyology Laboratory, Department of Ichthyology and Aquatic Environment, University of Thessaly, Fytokou Str., 38446 Volos, GreeceCryopreservation is a technique that offers various advantages, especially in fish, among others, that makes the reproduction of species easier through a constant supply of sperm, synchronization of the gamete availability of both sexes, storage of semen for genetic improvement programs, reduction in the cost by eliminating the need to maintain male broodstock, and conserving the gametes of endangered species. However, freezing and warming procedures for cryopreservation lead to a reduction in the quality and viability of cryopreserved sperm because of oxidative stress. For this reason, the enrichment of extender media with antioxidants is a common method of cryopreservation of the semen of several fish species. Recently, many studies have been published for the protective role of antioxidants and especially of melatonin on male fertility preservation both in farm animals and humans, demonstrating the beneficial effects of melatonin as a sperm cryoprotectant. On the other hand, very few studies were conducted using melatonin as an antioxidant in different male fish species for semen cryopreservation. We conclude that the use of moderate concentrations of melatonin are beneficial to semen preservation, and the mechanisms through which melatonin acts positively on spermatozoa need to be further investigated to establish improvement protocols for cryopreservation in fish species.https://www.mdpi.com/2076-2615/12/6/791cryopreservationfishfarm animalshumansemenmelatonin |
| spellingShingle | Alexandra I. Alevra Athanasios Exadactylos Eleni Mente Serafeim Papadopoulos The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation Animals cryopreservation fish farm animals human semen melatonin |
| title | The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation |
| title_full | The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation |
| title_fullStr | The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation |
| title_full_unstemmed | The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation |
| title_short | The Protective Role of Melatonin in Sperm Cryopreservation of Farm Animals and Human: Lessons for Male Fish Cryopreservation |
| title_sort | protective role of melatonin in sperm cryopreservation of farm animals and human lessons for male fish cryopreservation |
| topic | cryopreservation fish farm animals human semen melatonin |
| url | https://www.mdpi.com/2076-2615/12/6/791 |
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