Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19

It is widely known that COVID-19 has a number of prolonged effects on general health, wellbeing, and cognitive functioning. However, studies using differentiated performance measures of cognitive functions are still not widely spread making it hard to assess the exact functions that get impaired. Ta...

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Main Authors: Boris B. Velichkovsky, Anna Y. Razvaliaeva, Alena A. Khlebnikova, Piruza A. Manukyan, Vladimir N. Kasatkin, Artem V. Barmin
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2023/1094267
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author Boris B. Velichkovsky
Anna Y. Razvaliaeva
Alena A. Khlebnikova
Piruza A. Manukyan
Vladimir N. Kasatkin
Artem V. Barmin
author_facet Boris B. Velichkovsky
Anna Y. Razvaliaeva
Alena A. Khlebnikova
Piruza A. Manukyan
Vladimir N. Kasatkin
Artem V. Barmin
author_sort Boris B. Velichkovsky
collection DOAJ
description It is widely known that COVID-19 has a number of prolonged effects on general health, wellbeing, and cognitive functioning. However, studies using differentiated performance measures of cognitive functions are still not widely spread making it hard to assess the exact functions that get impaired. Taking into account the similarities between post-COVID ‘brain fog’ and chemofog, we hypothesized that executive functions (EF) would be impaired. Literature search yielded six studies with 14 effect sizes of interest; pooled effect size was small to medium (d=−0.35). Combined with a narrative synthesis of six studies without a comparison group, these results show that EF get impaired after COVID-19; although, in most cases the impairment is transient and does not seem to be severe. These results specify the picture of ‘brain fog’ and may help to discover its mechanisms and ways of helping people with long COVID.
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spelling doaj.art-9af03d2d65bd4befb90631e7f6f20dce2024-11-02T23:53:59ZengHindawi LimitedBehavioural Neurology1875-85842023-01-01202310.1155/2023/1094267Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19Boris B. Velichkovsky0Anna Y. Razvaliaeva1Alena A. Khlebnikova2Piruza A. Manukyan3Vladimir N. Kasatkin4Artem V. Barmin5Research Institute for Brain Development and Peak PerformanceInstitute of PsychologyLomonosov Moscow State UniversityResearch Institute for Brain Development and Peak PerformanceResearch Institute for Brain Development and Peak PerformanceCognitive Foundations of Communication LaboratoryIt is widely known that COVID-19 has a number of prolonged effects on general health, wellbeing, and cognitive functioning. However, studies using differentiated performance measures of cognitive functions are still not widely spread making it hard to assess the exact functions that get impaired. Taking into account the similarities between post-COVID ‘brain fog’ and chemofog, we hypothesized that executive functions (EF) would be impaired. Literature search yielded six studies with 14 effect sizes of interest; pooled effect size was small to medium (d=−0.35). Combined with a narrative synthesis of six studies without a comparison group, these results show that EF get impaired after COVID-19; although, in most cases the impairment is transient and does not seem to be severe. These results specify the picture of ‘brain fog’ and may help to discover its mechanisms and ways of helping people with long COVID.http://dx.doi.org/10.1155/2023/1094267
spellingShingle Boris B. Velichkovsky
Anna Y. Razvaliaeva
Alena A. Khlebnikova
Piruza A. Manukyan
Vladimir N. Kasatkin
Artem V. Barmin
Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19
Behavioural Neurology
title Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19
title_full Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19
title_fullStr Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19
title_full_unstemmed Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19
title_short Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19
title_sort systematic review and meta analysis of clinically relevant executive functions tests performance after covid 19
url http://dx.doi.org/10.1155/2023/1094267
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