Differential Toxicity of DNA Adducts of Mitomycin C

Differential Toxicity of DNA Adducts of Mitomycin C

The clinically used antitumor agent mitomycin C (MC) alkylates DNA upon reductive activation, forming six covalent DNA adducts in this process. This review focuses on differential biological effects of individual adducts in various mammalian cell cultures, observed in the authors' laboratories....

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Jill Bargonetti, Elise Champeil, Maria Tomasz
Format:	Artykuł
Język:	English
Wydane:	Wiley 2010-01-01
Seria:	Journal of Nucleic Acids
Dostęp online:	http://dx.doi.org/10.4061/2010/698960

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