Identification of a novel functional miR-143-5p recognition element in the Cystic Fibrosis Transmembrane Conductance Regulator 3’UTR

Identification of a novel functional miR-143-5p recognition element in the Cystic Fibrosis Transmembrane Conductance Regulator 3’UTR

MicroRNAs (miRNAs) are small non-coding RNAs involved in regulation of gene expression. They bind in a sequence-specific manner to miRNA recognition elements (MREs) located in the 3’ untranslated region (UTR) of target mRNAs and prevent mRNA translation. MiRNA expression is dysregulated in cystic fi...

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Bibliographic Details
Main Authors: Chiara De Santi, Sucharitha Gadi, Agnieszka Swiatecka-Urban, Catherine M. Greene
Format: Article
Language:English
Published: AIMS Press 2018-02-01
Series:AIMS Genetics
Subjects:
microRNA
cystic fibrosis
CFTR
qRT-PCR
luciferase assay
Online Access:http://www.aimspress.com/Genetics/article/1833/fulltext.html

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