Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland
Water-clear cell adenoma of the parathyroid gland is a rare neoplasm that consists of cells with abundant clear-pink cytoplasm. There have only been 19 cases reported in the English literature. Here we report a case of water-clear cell adenoma of the mediastinal parathyroid gland. A 70-year-old male...
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Format: | Article |
Language: | English |
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Federation of Turkish Pathology Societies
2019-05-01
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Series: | Türk Patoloji Dergisi |
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http://www.turkjpath.org/pdf.php3?id=1844
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author | Deniz ARIK Emine DÜNDAR Evrim YILMAZ Cumhur SİVRİKOZ |
author_facet | Deniz ARIK Emine DÜNDAR Evrim YILMAZ Cumhur SİVRİKOZ |
author_sort | Deniz ARIK |
collection | DOAJ |
description | Water-clear cell adenoma of the parathyroid gland is a rare neoplasm that consists of cells with abundant clear-pink cytoplasm. There have only been 19 cases reported in the English literature. Here we report a case of water-clear cell adenoma of the mediastinal parathyroid gland. A 70-year-old male patient presented to the hospital with back pain and a mediastinal mass 6 cm in size was detected. After excision and microscopic evaluation, uniform, large clear cells with fine cytoplasmic vacuolization, without nuclear atypia, and arranged in solid and acinar patterns were revealed. The cells formed nests that were separated by fine fibrovascular septae and stained positively with anti-parathyroid hormone. To the best of our knowledge, this has not been previously reported in this location. In the differential diagnosis of clear cell lesions of the mediastinum, water-clear cell parathyroid adenoma should be considered. |
first_indexed | 2024-04-10T14:56:46Z |
format | Article |
id | doaj.art-9af63ff1f0224ff4941aa255c496f212 |
institution | Directory Open Access Journal |
issn | 1018-5615 1309-5730 |
language | English |
last_indexed | 2024-04-10T14:56:46Z |
publishDate | 2019-05-01 |
publisher | Federation of Turkish Pathology Societies |
record_format | Article |
series | Türk Patoloji Dergisi |
spelling | doaj.art-9af63ff1f0224ff4941aa255c496f2122023-02-15T16:07:19ZengFederation of Turkish Pathology SocietiesTürk Patoloji Dergisi1018-56151309-57302019-05-0135215716110.5146/tjpath.2017.01407Water-Clear Cell Adenoma of the Mediastinal Parathyroid GlandDeniz ARIKEmine DÜNDAREvrim YILMAZCumhur SİVRİKOZWater-clear cell adenoma of the parathyroid gland is a rare neoplasm that consists of cells with abundant clear-pink cytoplasm. There have only been 19 cases reported in the English literature. Here we report a case of water-clear cell adenoma of the mediastinal parathyroid gland. A 70-year-old male patient presented to the hospital with back pain and a mediastinal mass 6 cm in size was detected. After excision and microscopic evaluation, uniform, large clear cells with fine cytoplasmic vacuolization, without nuclear atypia, and arranged in solid and acinar patterns were revealed. The cells formed nests that were separated by fine fibrovascular septae and stained positively with anti-parathyroid hormone. To the best of our knowledge, this has not been previously reported in this location. In the differential diagnosis of clear cell lesions of the mediastinum, water-clear cell parathyroid adenoma should be considered. http://www.turkjpath.org/pdf.php3?id=1844 Water-clear cellAdenomaEctopic tissueMediastinumParathyroid gland |
spellingShingle | Deniz ARIK Emine DÜNDAR Evrim YILMAZ Cumhur SİVRİKOZ Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland Türk Patoloji Dergisi Water-clear cell Adenoma Ectopic tissue Mediastinum Parathyroid gland |
title | Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland |
title_full | Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland |
title_fullStr | Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland |
title_full_unstemmed | Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland |
title_short | Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland |
title_sort | water clear cell adenoma of the mediastinal parathyroid gland |
topic | Water-clear cell Adenoma Ectopic tissue Mediastinum Parathyroid gland |
url |
http://www.turkjpath.org/pdf.php3?id=1844
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work_keys_str_mv | AT denizarik waterclearcelladenomaofthemediastinalparathyroidgland AT eminedundar waterclearcelladenomaofthemediastinalparathyroidgland AT evrimyilmaz waterclearcelladenomaofthemediastinalparathyroidgland AT cumhursivrikoz waterclearcelladenomaofthemediastinalparathyroidgland |