Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review

This paper provides an in-depth overview of Deep Neural Networks and their application in the segmentation and analysis of lung Magnetic Resonance Imaging (MRI) scans, specifically focusing on hyperpolarized gas MRI and the quantification of lung ventilation defects. An in-depth understanding of Dee...

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Main Authors: Ramtin Babaeipour, Alexei Ouriadov, Matthew S. Fox
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/12/1349
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author Ramtin Babaeipour
Alexei Ouriadov
Matthew S. Fox
author_facet Ramtin Babaeipour
Alexei Ouriadov
Matthew S. Fox
author_sort Ramtin Babaeipour
collection DOAJ
description This paper provides an in-depth overview of Deep Neural Networks and their application in the segmentation and analysis of lung Magnetic Resonance Imaging (MRI) scans, specifically focusing on hyperpolarized gas MRI and the quantification of lung ventilation defects. An in-depth understanding of Deep Neural Networks is presented, laying the groundwork for the exploration of their use in hyperpolarized gas MRI and the quantification of lung ventilation defects. Five distinct studies are examined, each leveraging unique deep learning architectures and data augmentation techniques to optimize model performance. These studies encompass a range of approaches, including the use of 3D Convolutional Neural Networks, cascaded U-Net models, Generative Adversarial Networks, and nnU-net for hyperpolarized gas MRI segmentation. The findings highlight the potential of deep learning methods in the segmentation and analysis of lung MRI scans, emphasizing the need for consensus on lung ventilation segmentation methods.
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spelling doaj.art-9af8a15f715641059f136c8646ac87862023-12-22T13:53:58ZengMDPI AGBioengineering2306-53542023-11-011012134910.3390/bioengineering10121349Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A ReviewRamtin Babaeipour0Alexei Ouriadov1Matthew S. Fox2School of Biomedical Engineering, Faculty of Engineering, The University of Western Ontario, London, ON N6A 3K7, CanadaSchool of Biomedical Engineering, Faculty of Engineering, The University of Western Ontario, London, ON N6A 3K7, CanadaDepartment of Physics and Astronomy, The University of Western Ontario, London, ON N6A 3K7, CanadaThis paper provides an in-depth overview of Deep Neural Networks and their application in the segmentation and analysis of lung Magnetic Resonance Imaging (MRI) scans, specifically focusing on hyperpolarized gas MRI and the quantification of lung ventilation defects. An in-depth understanding of Deep Neural Networks is presented, laying the groundwork for the exploration of their use in hyperpolarized gas MRI and the quantification of lung ventilation defects. Five distinct studies are examined, each leveraging unique deep learning architectures and data augmentation techniques to optimize model performance. These studies encompass a range of approaches, including the use of 3D Convolutional Neural Networks, cascaded U-Net models, Generative Adversarial Networks, and nnU-net for hyperpolarized gas MRI segmentation. The findings highlight the potential of deep learning methods in the segmentation and analysis of lung MRI scans, emphasizing the need for consensus on lung ventilation segmentation methods.https://www.mdpi.com/2306-5354/10/12/1349deep learningMagnetic Resonance Imaging (MRI)hyperpolarized gas MRIsegmentationventilation defectchronic obstructive pulmonary disease (COPD)
spellingShingle Ramtin Babaeipour
Alexei Ouriadov
Matthew S. Fox
Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review
Bioengineering
deep learning
Magnetic Resonance Imaging (MRI)
hyperpolarized gas MRI
segmentation
ventilation defect
chronic obstructive pulmonary disease (COPD)
title Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review
title_full Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review
title_fullStr Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review
title_full_unstemmed Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review
title_short Deep Learning Approaches for Quantifying Ventilation Defects in Hyperpolarized Gas Magnetic Resonance Imaging of the Lung: A Review
title_sort deep learning approaches for quantifying ventilation defects in hyperpolarized gas magnetic resonance imaging of the lung a review
topic deep learning
Magnetic Resonance Imaging (MRI)
hyperpolarized gas MRI
segmentation
ventilation defect
chronic obstructive pulmonary disease (COPD)
url https://www.mdpi.com/2306-5354/10/12/1349
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