Timosaponin-BII inhibits the up-regulation of BACE1 induced by Ferric Chloride in rat retina

Timosaponin-BII inhibits the up-regulation of BACE1 induced by Ferric Chloride in rat retina

<p>Abstract</p> <p>Background</p> <p>Our previous studies indicated that oxidative stress up-regulated the expression of β-amyloid precursor protein cleavage enzyme-1 (BACE1) in rat retina. Pharmacological reports have shown Timosaponin-BII, a purified extract originati...

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Bibliographic Details
Main Authors: Huang Ju-Fang, Shang Lei, Liu Pei, Zhang Meng-Qi, Chen Shuang, Chen Dan, Fan Chun-Ling, Wang Hui, Xiong Kun
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Timosaponin-BII
Oxidative stress
BACE1
Retina
Aβ
Online Access:http://www.biomedcentral.com/1472-6882/12/189

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