GABA<sub>A</sub> and Glycine Receptor-Mediated Inhibitory Synaptic Transmission onto Adult Rat Lamina II<sub>i</sub> PKCγ-Interneurons: Pharmacological but Not Anatomical Specialization

GABA<sub>A</sub> and Glycine Receptor-Mediated Inhibitory Synaptic Transmission onto Adult Rat Lamina II<sub>i</sub> PKCγ-Interneurons: Pharmacological but Not Anatomical Specialization

Mechanical allodynia (pain to normally innocuous tactile stimuli) is a widespread symptom of inflammatory and neuropathic pain. Spinal or medullary dorsal horn (SDH or MDH) circuits mediating tactile sensation and pain need to interact in order to evoke mechanical allodynia. PKCγ-expressing (PKCγ<...

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Bibliographic Details
Main Authors: Corinne El Khoueiry, Cristina Alba-Delgado, Myriam Antri, Maria Gutierrez-Mecinas, Andrew J. Todd, Alain Artola, Radhouane Dallel
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
mechanical allodynia
medullary dorsal horn
protein kinase C gamma
inhibitory interneurons
spontaneous IPSCs
miniature IPSCs
Online Access:https://www.mdpi.com/2073-4409/11/8/1356

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