Development of a facile method to compute collagen network pathological anisotropy using AFM imaging

Abstract Type I collagen, a fundamental extracellular matrix (ECM) component, is pivotal in maintaining tissue integrity and strength. It is also the most prevalent fibrous biopolymer within the ECM, ubiquitous in mammalian organisms. This structural protein provides essential mechanical stability a...

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Bibliographic Details
Main Authors: Emilie Khattignavong, Mehrnoosh Neshatian, Mina Vaez, Amaury Guillermin, Josephine T. Tauer, Marianne Odlyha, Nimish Mittal, Svetlana V. Komarova, Hassan Zahouani, Laurent Bozec
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47350-y