Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors Following Neonatal Hypoxia-Ischemia

Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors Following Neonatal Hypoxia-Ischemia

In this study we assessed the importance of insulin-like growth factor (IGF) and epidermal growth factor (EGF) receptor co-signaling for rat neural precursor (NP) cell proliferation and self-renewal in the context of a developmental brain injury that is associated with cerebral palsy. Consistent wit...

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Bibliographic Details
Main Authors: Dhivyaa eAlagappan, Amber N. Ziegler, Shravanthi eChidambaram, Jungsoo eMin, Teresa L. Wood, Steven W. Levison
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Neurology
Subjects:
Cell Proliferation
Central Nervous System
Regeneration
Stem Cell Niche
growth factors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00079/full

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