Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
Feyzahan Ekici, Marlene R Moster, Victor Cvintal, Wanda D Hu, Michael Waisbourd Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, USA Purpose: To investigate the clinical outcomes of tube shunt coverage using sterile gamma-irradiated cornea allograft.Patients and methods: The Wills E...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2015-04-01
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| Series: | Clinical Ophthalmology |
| Online Access: | http://www.dovepress.com/tube-shunt-coverage-with-gamma-irradiated-cornea-allograft-visiongraft-peer-reviewed-article-OPTH |
| _version_ | 1818754472690581504 |
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| author | Ekici F Moster MR Cvintal V Hu WD Waisbourd M |
| author_facet | Ekici F Moster MR Cvintal V Hu WD Waisbourd M |
| author_sort | Ekici F |
| collection | DOAJ |
| description | Feyzahan Ekici, Marlene R Moster, Victor Cvintal, Wanda D Hu, Michael Waisbourd Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, USA Purpose: To investigate the clinical outcomes of tube shunt coverage using sterile gamma-irradiated cornea allograft.Patients and methods: The Wills Eye Hospital Glaucoma Research Center retrospectively reviewed the medical records of 165 patients who underwent glaucoma tube shunt procedures using sterile gamma-irradiated cornea allograft (VisionGraft) between December 2012 and November 2013. Demographic characteristics, type of tube shunt, and position were noted. Complications were recorded at 1 day; 1 week; 1, 3, 6, and 12 months; and on the final postoperative visit.Results: One hundred and sixty-nine eyes of 165 patients were included. The mean follow-up time was 4.8±3.5 (ranging from 1 to 16) months. There was no evidence of immunological reaction, infection, or exposure in 166 eyes (98.2%). Three eyes (1.8%) experienced graft or tube exposure within the first 3 postoperative months. Two of the cases had underlying diseases: bullous pemphigoid and chronic allergic conjunctivitis.Conclusion: Coverage of tube shunts using gamma-irradiated cornea allograft had a low exposure rate and was well tolerated. The graft can be stored long term at room temperature and has an excellent postoperative cosmetic appearance.Keywords: aqueous shunts, gamma-irradiated cornea allograft, glaucoma drainage device, tube shunt surgery |
| first_indexed | 2024-12-18T05:23:48Z |
| format | Article |
| id | doaj.art-9b02e94200bf4ec8bfbc6273c9f2a88e |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-18T05:23:48Z |
| publishDate | 2015-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-9b02e94200bf4ec8bfbc6273c9f2a88e2022-12-21T21:19:35ZengDove Medical PressClinical Ophthalmology1177-54832015-04-012015default75175521516Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)Ekici FMoster MRCvintal VHu WDWaisbourd MFeyzahan Ekici, Marlene R Moster, Victor Cvintal, Wanda D Hu, Michael Waisbourd Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, USA Purpose: To investigate the clinical outcomes of tube shunt coverage using sterile gamma-irradiated cornea allograft.Patients and methods: The Wills Eye Hospital Glaucoma Research Center retrospectively reviewed the medical records of 165 patients who underwent glaucoma tube shunt procedures using sterile gamma-irradiated cornea allograft (VisionGraft) between December 2012 and November 2013. Demographic characteristics, type of tube shunt, and position were noted. Complications were recorded at 1 day; 1 week; 1, 3, 6, and 12 months; and on the final postoperative visit.Results: One hundred and sixty-nine eyes of 165 patients were included. The mean follow-up time was 4.8±3.5 (ranging from 1 to 16) months. There was no evidence of immunological reaction, infection, or exposure in 166 eyes (98.2%). Three eyes (1.8%) experienced graft or tube exposure within the first 3 postoperative months. Two of the cases had underlying diseases: bullous pemphigoid and chronic allergic conjunctivitis.Conclusion: Coverage of tube shunts using gamma-irradiated cornea allograft had a low exposure rate and was well tolerated. The graft can be stored long term at room temperature and has an excellent postoperative cosmetic appearance.Keywords: aqueous shunts, gamma-irradiated cornea allograft, glaucoma drainage device, tube shunt surgery http://www.dovepress.com/tube-shunt-coverage-with-gamma-irradiated-cornea-allograft-visiongraft-peer-reviewed-article-OPTH |
| spellingShingle | Ekici F Moster MR Cvintal V Hu WD Waisbourd M Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft) Clinical Ophthalmology |
| title | Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft) |
| title_full | Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft) |
| title_fullStr | Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft) |
| title_full_unstemmed | Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft) |
| title_short | Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft) |
| title_sort | tube shunt coverage with gamma irradiated cornea allograft visiongraft |
| url | http://www.dovepress.com/tube-shunt-coverage-with-gamma-irradiated-cornea-allograft-visiongraft-peer-reviewed-article-OPTH |
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