Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina
Aim Recently increased attention and interest for Acinetobacterbaumannii are the result of the occurrence of multidrug resistant (MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates t...
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| Format: | Article |
| Language: | English |
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Medical Association of Zenica-Doboj Canton
2015-08-01
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| Series: | Medicinski Glasnik |
| Subjects: | |
| Online Access: | http://ljkzedo.ba/sites/default/files/Glasnik/MG23/10%20amela%20dedeic-ljubovic.pdf |
| _version_ | 1819268248534777856 |
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| author | Amela Dedeić-Ljubović Ðana Granov Mirsada Hukić |
| author_facet | Amela Dedeić-Ljubović Ðana Granov Mirsada Hukić |
| author_sort | Amela Dedeić-Ljubović |
| collection | DOAJ |
| description | Aim Recently increased attention and interest for Acinetobacterbaumannii are the result of the occurrence of multidrug resistant (MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates to antimicrobials in Clinical Centre University of Sarajevo, Bosnia and Herzegovina.
Methods Two hundred and fifty-seven A.baumannii isolates were collected between July 2011 and June 2012 in different wards and from different clinical samples. Multidrug resistant, XDR and PDR were defined according to international expert proposal for interim standard definitions for acquired resistance.
Results A total of 257 A. baumannii isolates showed eleven different patterns of resistance, of which ten patterns corresponded to MDR and one corresponded to XDR (sensitive only to colistin). Multidrug resistant and XDR strains were the most common at Intensive Care Units and surgical departments. The largest numbers of isolates were found in wound swabs, blood and bronchial aspirate.
Conclusion This is the first report of XDR A. baumannii in the 2000-bed Clinical Centre University of Sarajevo, Bosnia-Herzegovina. Although XDR strains have been detected, the resistance to colistin has not. The elevated prevalence of these strains indicates that local antibiotic prescription policies should be revised and infection prevention and control should be improved. |
| first_indexed | 2024-12-23T21:30:03Z |
| format | Article |
| id | doaj.art-9b0cba9f26ce4ed0a199563c5d5c2f32 |
| institution | Directory Open Access Journal |
| issn | 1840-0132 1840-2445 |
| language | English |
| last_indexed | 2024-12-23T21:30:03Z |
| publishDate | 2015-08-01 |
| publisher | Medical Association of Zenica-Doboj Canton |
| record_format | Article |
| series | Medicinski Glasnik |
| spelling | doaj.art-9b0cba9f26ce4ed0a199563c5d5c2f322022-12-21T17:30:29ZengMedical Association of Zenica-Doboj CantonMedicinski Glasnik1840-01321840-24452015-08-0112216917610.17392/809-15Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and HerzegovinaAmela Dedeić-Ljubović0Ðana Granov1Mirsada Hukić2Department of Clinical microbiology, Clinical Centre University of SarajevoDepartment of Clinical microbiology, Clinical Centre University of SarajevoDepartment of Medical Science, Academy of Sciences and Arts of Bosnia and Herzegovina; International Burch University, Sarajevo, Bosnia and HerzegovinaAim Recently increased attention and interest for Acinetobacterbaumannii are the result of the occurrence of multidrug resistant (MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates to antimicrobials in Clinical Centre University of Sarajevo, Bosnia and Herzegovina. Methods Two hundred and fifty-seven A.baumannii isolates were collected between July 2011 and June 2012 in different wards and from different clinical samples. Multidrug resistant, XDR and PDR were defined according to international expert proposal for interim standard definitions for acquired resistance. Results A total of 257 A. baumannii isolates showed eleven different patterns of resistance, of which ten patterns corresponded to MDR and one corresponded to XDR (sensitive only to colistin). Multidrug resistant and XDR strains were the most common at Intensive Care Units and surgical departments. The largest numbers of isolates were found in wound swabs, blood and bronchial aspirate. Conclusion This is the first report of XDR A. baumannii in the 2000-bed Clinical Centre University of Sarajevo, Bosnia-Herzegovina. Although XDR strains have been detected, the resistance to colistin has not. The elevated prevalence of these strains indicates that local antibiotic prescription policies should be revised and infection prevention and control should be improved.http://ljkzedo.ba/sites/default/files/Glasnik/MG23/10%20amela%20dedeic-ljubovic.pdfantimicrobialsnosocomial infectionsintensive care unit |
| spellingShingle | Amela Dedeić-Ljubović Ðana Granov Mirsada Hukić Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina Medicinski Glasnik antimicrobials nosocomial infections intensive care unit |
| title | Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina |
| title_full | Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina |
| title_fullStr | Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina |
| title_full_unstemmed | Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina |
| title_short | Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina |
| title_sort | emergence of extensive drug resistant xdr acinetobacter baumanniiin the clinical center university of sarajevo bosnia and herzegovina |
| topic | antimicrobials nosocomial infections intensive care unit |
| url | http://ljkzedo.ba/sites/default/files/Glasnik/MG23/10%20amela%20dedeic-ljubovic.pdf |
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