Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling

Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling

Tissue homeostasis and regeneration in the Drosophila midgut is regulated by a diverse array of signaling pathways including the Hippo pathway. Hippo signaling restricts intestinal stem cell (ISC) proliferation by sequestering the transcription co-factor Yorkie (Yki) in the cytoplasm, a factor requi...

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Bibliographic Details
Main Authors: Xue Hao, Shimin Wang, Yi Lu, Wentao Yu, Pengyue Li, Dan Jiang, Tong Guo, Mengjie Li, Jinhui Li, Jinjin Xu, Wenqing Wu, Margaret S Ho, Lei Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
drosophila adult midgut
Hippo signaling
Lola
ISC proliferation
tissue homeostasis
Warts
Online Access:https://elifesciences.org/articles/47542

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