Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition
There is a strong relationship between a healthy diet and mental well-being. Several foods and food compounds are known to modulate biomarkers and molecular mechanisms involved in the aetiogenesis of several mental disorders, and this can be useful in containing the disease progression, including it...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-05-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.565583/full |
| _version_ | 1818457048301436928 |
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| author | Samuel J. Offor Chinna N. Orish Chiara Frazzoli Orish E. Orisakwe Orish E. Orisakwe |
| author_facet | Samuel J. Offor Chinna N. Orish Chiara Frazzoli Orish E. Orisakwe Orish E. Orisakwe |
| author_sort | Samuel J. Offor |
| collection | DOAJ |
| description | There is a strong relationship between a healthy diet and mental well-being. Several foods and food compounds are known to modulate biomarkers and molecular mechanisms involved in the aetiogenesis of several mental disorders, and this can be useful in containing the disease progression, including its prophylaxis. This is an updated systematic review of the literature to justify the inclusion and recognition of nutrition in the management of psychiatric illnesses. Such foods and their compounds include dietary flavanols from fruits and vegetables, notable antioxidant and anti-inflammatory agents, probiotics (fermented foods) known to protect good gut bacteria, foods rich in polyunsaturated fatty acids (e.g., Omega-3), and avoiding diets high in saturated fats and refined sugars among others. While the exact mechanism(s) of mitigation of many nutritional interventions are yet to be fully understood, the evidence-based approach warrants the inclusion and co-recognition of nutrition in the management of psychiatric illnesses. For the greater public health benefit, there is a need for policy advocacy aimed at bridging the knowledge gap and encouraging the integration of nutritional intervention with contemporary therapies in clinical settings, as deficiencies of certain nutrients make therapy difficult even with appropriate medication. |
| first_indexed | 2024-12-14T22:36:22Z |
| format | Article |
| id | doaj.art-9b127816349741618c22a0f90403eb73 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-14T22:36:22Z |
| publishDate | 2021-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-9b127816349741618c22a0f90403eb732022-12-21T22:45:08ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402021-05-011210.3389/fpsyt.2021.565583565583Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on NutritionSamuel J. Offor0Chinna N. Orish1Chiara Frazzoli2Orish E. Orisakwe3Orish E. Orisakwe4Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, NigeriaDepartment of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Port Harcourt, NigeriaDepartment of Cardiovascular and Endocrine-Metabolic Diseases, and Aging, Istituto Superiore di Sanità, Rome, ItalyDepartment of Experimental Pharmacology & Toxicology, Faculty of Pharmacy, University of Port Harcourt, Port Harcourt, NigeriaAfrican Centre of Excellence for Public Health and Toxicological Research (ACE-PUTOR), University of Port Harcourt, Port Harcourt, NigeriaThere is a strong relationship between a healthy diet and mental well-being. Several foods and food compounds are known to modulate biomarkers and molecular mechanisms involved in the aetiogenesis of several mental disorders, and this can be useful in containing the disease progression, including its prophylaxis. This is an updated systematic review of the literature to justify the inclusion and recognition of nutrition in the management of psychiatric illnesses. Such foods and their compounds include dietary flavanols from fruits and vegetables, notable antioxidant and anti-inflammatory agents, probiotics (fermented foods) known to protect good gut bacteria, foods rich in polyunsaturated fatty acids (e.g., Omega-3), and avoiding diets high in saturated fats and refined sugars among others. While the exact mechanism(s) of mitigation of many nutritional interventions are yet to be fully understood, the evidence-based approach warrants the inclusion and co-recognition of nutrition in the management of psychiatric illnesses. For the greater public health benefit, there is a need for policy advocacy aimed at bridging the knowledge gap and encouraging the integration of nutritional intervention with contemporary therapies in clinical settings, as deficiencies of certain nutrients make therapy difficult even with appropriate medication.https://www.frontiersin.org/articles/10.3389/fpsyt.2021.565583/fullpsychiatrymental disordermicrobiomebiomarkerprobioticsnutrition |
| spellingShingle | Samuel J. Offor Chinna N. Orish Chiara Frazzoli Orish E. Orisakwe Orish E. Orisakwe Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition Frontiers in Psychiatry psychiatry mental disorder microbiome biomarker probiotics nutrition |
| title | Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition |
| title_full | Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition |
| title_fullStr | Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition |
| title_full_unstemmed | Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition |
| title_short | Augmenting Clinical Interventions in Psychiatric Disorders: Systematic Review and Update on Nutrition |
| title_sort | augmenting clinical interventions in psychiatric disorders systematic review and update on nutrition |
| topic | psychiatry mental disorder microbiome biomarker probiotics nutrition |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.565583/full |
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