Leptin/obR signaling exacerbates obesity-related neutrophilic airway inflammation through inflammatory M1 macrophages
Abstract Background Obesity-related asthma is a kind of nonallergic asthma with excessive neutrophil infiltration in the airways. However, the underlying mechanisms have been poorly elucidated. Among the adipokines related to obesity, leptin is related to the inflammatory response. However, little i...
Main Authors: | Yang Wang, Rongjun Wan, Chengping Hu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
|
Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10020-023-00702-w |
Similar Items
-
Leptin and leptin receptor gene polymorphisms in obese and healthy children
by: Gönül Çatlı, et al.
Published: (2022-03-01) -
Original paper The effect of leptin on the respiratory burst of human neutrophils cultured in synovial fluid
by: Michał Gajewski, et al.
Published: (2015-04-01) -
Leptin signaling and leptin resistance
by: Liu Jiarui, et al.
Published: (2022-08-01) -
New pharmacological perspectives for the leptin receptor in the treatment of obesity
by: Clara eRoujeau, et al.
Published: (2014-10-01) -
Editorial: Leptin, obesity and diet at a glance
by: Deanne H. Hryciw, et al.
Published: (2022-11-01)