Unsupervised Learning for Feature Representation Using Spatial Distribution of Amino Acids in Aldehyde Dehydrogenase (ALDH2) Protein Sequences

Unsupervised Learning for Feature Representation Using Spatial Distribution of Amino Acids in Aldehyde Dehydrogenase (ALDH2) Protein Sequences

Aldehyde dehydrogenase 2 (ALDH2) enzyme is required for alcohol detoxification. ALDH2 belongs to the aldehyde dehydrogenase family, the most important oxidative pathway of alcohol digestion. Two main liver isoforms of aldehyde dehydrogenase are cytosolic and mitochondrial. Approximately 50% of East...

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Bibliographic Details
Main Authors: Monika Khandelwal, Sabha Sheikh, Ranjeet Kumar Rout, Saiyed Umer, Saurav Mallik, Zhongming Zhao
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Mathematics
Subjects:
aldehyde dehydrogenase 2
ethanol metabolism
machine learning
physicochemical properties
secondary structure
Online Access:https://www.mdpi.com/2227-7390/10/13/2228

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