Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation

Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation

Abstract Neuronal dysfunction and loss associated with the accumulation of amyloid-β (Aβ) in the form of extracellular amyloid plaques and hyperphosphorylated tau in the form of intraneuronal neurofibrillary tangles represent key features of Alzheimer’s disease (AD). Amyloid plaques found in the bra...

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Bibliographic Details
Main Authors: O. G. Zatsepina, O. I. Kechko, V. A. Mitkevich, S. A. Kozin, M. M. Yurinskaya, M. G. Vinokurov, M. V. Serebryakova, A. P. Rezvykh, M. B. Evgen’ev, A. A. Makarov
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21815-x

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