Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering
Induced pluripotent stem cells (iPSCs) are essentially produced by the genetic reprogramming of adult cells. Moreover, iPSC technology prevents the genetic manipulation of embryos. Hence, with the ensured element of safety, they rarely cause ethical concerns when utilized in tissue engineering. Seve...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/13/2/155 |
| _version_ | 1797478004296777728 |
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| author | Arvind Kumar Shukla Ge Gao Byoung Soo Kim |
| author_facet | Arvind Kumar Shukla Ge Gao Byoung Soo Kim |
| author_sort | Arvind Kumar Shukla |
| collection | DOAJ |
| description | Induced pluripotent stem cells (iPSCs) are essentially produced by the genetic reprogramming of adult cells. Moreover, iPSC technology prevents the genetic manipulation of embryos. Hence, with the ensured element of safety, they rarely cause ethical concerns when utilized in tissue engineering. Several cumulative outcomes have demonstrated the functional superiority and potency of iPSCs in advanced regenerative medicine. Recently, an emerging trend in 3D bioprinting technology has been a more comprehensive approach to iPSC-based tissue engineering. The principal aim of this review is to provide an understanding of the applications of 3D bioprinting in iPSC-based tissue engineering. This review discusses the generation of iPSCs based on their distinct purpose, divided into two categories: (1) undifferentiated iPSCs applied with 3D bioprinting; (2) differentiated iPSCs applied with 3D bioprinting. Their significant potential is analyzed. Lastly, various applications for engineering tissues and organs have been introduced and discussed in detail. |
| first_indexed | 2024-03-09T21:25:52Z |
| format | Article |
| id | doaj.art-9b1545b13b6447d49309e5febeed4c4f |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-09T21:25:52Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-9b1545b13b6447d49309e5febeed4c4f2023-11-23T21:09:28ZengMDPI AGMicromachines2072-666X2022-01-0113215510.3390/mi13020155Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue EngineeringArvind Kumar Shukla0Ge Gao1Byoung Soo Kim2School of Biomedical Convergence Engineering, Pusan National University, Yangsan 50612, KoreaInstitute of Engineering Medicine, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Biomedical Convergence Engineering, Pusan National University, Yangsan 50612, KoreaInduced pluripotent stem cells (iPSCs) are essentially produced by the genetic reprogramming of adult cells. Moreover, iPSC technology prevents the genetic manipulation of embryos. Hence, with the ensured element of safety, they rarely cause ethical concerns when utilized in tissue engineering. Several cumulative outcomes have demonstrated the functional superiority and potency of iPSCs in advanced regenerative medicine. Recently, an emerging trend in 3D bioprinting technology has been a more comprehensive approach to iPSC-based tissue engineering. The principal aim of this review is to provide an understanding of the applications of 3D bioprinting in iPSC-based tissue engineering. This review discusses the generation of iPSCs based on their distinct purpose, divided into two categories: (1) undifferentiated iPSCs applied with 3D bioprinting; (2) differentiated iPSCs applied with 3D bioprinting. Their significant potential is analyzed. Lastly, various applications for engineering tissues and organs have been introduced and discussed in detail.https://www.mdpi.com/2072-666X/13/2/155induced pluripotent stem cells (iPSCs)3D bioprinting |
| spellingShingle | Arvind Kumar Shukla Ge Gao Byoung Soo Kim Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering Micromachines induced pluripotent stem cells (iPSCs) 3D bioprinting |
| title | Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering |
| title_full | Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering |
| title_fullStr | Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering |
| title_full_unstemmed | Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering |
| title_short | Applications of 3D Bioprinting Technology in Induced Pluripotent Stem Cells-Based Tissue Engineering |
| title_sort | applications of 3d bioprinting technology in induced pluripotent stem cells based tissue engineering |
| topic | induced pluripotent stem cells (iPSCs) 3D bioprinting |
| url | https://www.mdpi.com/2072-666X/13/2/155 |
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