A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery

Summary:. Development of human-compatible tissues is an active field of research that is leading to the production of optimized biological scaffolds to support regenerative medicine. Xenogenic acellular matrices are known to have strongly influenced the field of breast surgery, playing an integral r...

Full description

Bibliographic Details
Main Authors: Renato Muccioli Casadei, MD, Maria Elena Corezzola, MD, Andrea Monticelli, MD
Format: Article
Language:English
Published: Wolters Kluwer 2024-02-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005628
_version_ 1797292766974181376
author Renato Muccioli Casadei, MD
Maria Elena Corezzola, MD
Andrea Monticelli, MD
author_facet Renato Muccioli Casadei, MD
Maria Elena Corezzola, MD
Andrea Monticelli, MD
author_sort Renato Muccioli Casadei, MD
collection DOAJ
description Summary:. Development of human-compatible tissues is an active field of research that is leading to the production of optimized biological scaffolds to support regenerative medicine. Xenogenic acellular matrices are known to have strongly influenced the field of breast surgery, playing an integral role in wound healing and in preventing the foreign body reaction to silicone implants. Here, we present our experience in using a biological matrix for aesthetic revision surgery with malposition and severe capsular contracture. Revisions were performed using the new MASQUE equine acellular-pericardium-matrix (APM) as an anterior cover for the synthetic prosthesis. Acting as an internal support, the thin APM layer provides a biological and biocompatible interface between the synthetic implant and living tissues, exerting a protective function against fibrotic responses and capsular contracture. The role of an APM in matrix-assisted mammoplasty has yet to be fully established. Our early experience of APM-assisted aesthetic revision surgery shows promising results, laying the foundations for equine biological matrices as a valid tool for the management of capsular contracture-susceptible patients.
first_indexed 2024-03-07T20:02:18Z
format Article
id doaj.art-9b162496ae2f4616b98c5a7004a9de55
institution Directory Open Access Journal
issn 2169-7574
language English
last_indexed 2024-03-07T20:02:18Z
publishDate 2024-02-01
publisher Wolters Kluwer
record_format Article
series Plastic and Reconstructive Surgery, Global Open
spelling doaj.art-9b162496ae2f4616b98c5a7004a9de552024-02-28T06:48:01ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742024-02-01122e562810.1097/GOX.0000000000005628202402000-00062A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision SurgeryRenato Muccioli Casadei, MD0Maria Elena Corezzola, MD1Andrea Monticelli, MD2From Medica Uno Venice Surgery, Venice, Italy.From Medica Uno Venice Surgery, Venice, Italy.From Medica Uno Venice Surgery, Venice, Italy.Summary:. Development of human-compatible tissues is an active field of research that is leading to the production of optimized biological scaffolds to support regenerative medicine. Xenogenic acellular matrices are known to have strongly influenced the field of breast surgery, playing an integral role in wound healing and in preventing the foreign body reaction to silicone implants. Here, we present our experience in using a biological matrix for aesthetic revision surgery with malposition and severe capsular contracture. Revisions were performed using the new MASQUE equine acellular-pericardium-matrix (APM) as an anterior cover for the synthetic prosthesis. Acting as an internal support, the thin APM layer provides a biological and biocompatible interface between the synthetic implant and living tissues, exerting a protective function against fibrotic responses and capsular contracture. The role of an APM in matrix-assisted mammoplasty has yet to be fully established. Our early experience of APM-assisted aesthetic revision surgery shows promising results, laying the foundations for equine biological matrices as a valid tool for the management of capsular contracture-susceptible patients.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005628
spellingShingle Renato Muccioli Casadei, MD
Maria Elena Corezzola, MD
Andrea Monticelli, MD
A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery
Plastic and Reconstructive Surgery, Global Open
title A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery
title_full A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery
title_fullStr A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery
title_full_unstemmed A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery
title_short A High-biocompatibility Interface for the Breast Implant: First Report of a Novel Biological Matrix–assisted Technique in Aesthetic Revision Surgery
title_sort high biocompatibility interface for the breast implant first report of a novel biological matrix assisted technique in aesthetic revision surgery
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005628
work_keys_str_mv AT renatomucciolicasadeimd ahighbiocompatibilityinterfaceforthebreastimplantfirstreportofanovelbiologicalmatrixassistedtechniqueinaestheticrevisionsurgery
AT mariaelenacorezzolamd ahighbiocompatibilityinterfaceforthebreastimplantfirstreportofanovelbiologicalmatrixassistedtechniqueinaestheticrevisionsurgery
AT andreamonticellimd ahighbiocompatibilityinterfaceforthebreastimplantfirstreportofanovelbiologicalmatrixassistedtechniqueinaestheticrevisionsurgery
AT renatomucciolicasadeimd highbiocompatibilityinterfaceforthebreastimplantfirstreportofanovelbiologicalmatrixassistedtechniqueinaestheticrevisionsurgery
AT mariaelenacorezzolamd highbiocompatibilityinterfaceforthebreastimplantfirstreportofanovelbiologicalmatrixassistedtechniqueinaestheticrevisionsurgery
AT andreamonticellimd highbiocompatibilityinterfaceforthebreastimplantfirstreportofanovelbiologicalmatrixassistedtechniqueinaestheticrevisionsurgery