Sox2 Level Is a Determinant of Cellular Reprogramming Potential.

Sox2 Level Is a Determinant of Cellular Reprogramming Potential.

Epiblast stem cells (EpiSCs) and embryonic stem cells (ESCs) differ in their in vivo differentiation potential. While ESCs form teratomas and efficiently contribute to the development of chimeras, EpiSCs form teratomas but very rarely chimeras. In contrast to their differentiation potential, the rep...

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Bibliographic Details
Main Authors: Dong Wook Han, Natalia Tapia, Marcos J Araúzo-Bravo, Kyung Tae Lim, Kee Pyo Kim, Kinarm Ko, Hoon Taek Lee, Hans R Schöler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688988?pdf=render

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