The role of STriatal-Enriched protein tyrosine Phosphastase (STEP) in cognition
STriatal-Enriched protein tyrosine Phosphatase (STEP) has recently been implicated in several neuropsychiatric disorders with significant cognitive impairments, including Alzheimer’s disease, schizophrenia, and fragile X syndrome. A model has emerged by which STEP normally opposes the development of...
Main Authors: | Christopher James Fitzpatrick, Paul J Lombroso |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-07-01
|
Series: | Frontiers in Neuroanatomy |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnana.2011.00047/full |
Similar Items
-
Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking.
by: Rémi Legastelois, et al.
Published: (2015-01-01) -
Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)
by: Lester J Lambert, et al.
Published: (2021-04-01) -
The current "next step" in neuropsychiatric disorders studies
by: Lombroso Paul J., et al.
Published: (2002-01-01) -
PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning
by: Timothy Johanssen, et al.
Published: (2015-09-01) -
Rat cortico-striatal sagittal organotypic slice cultures as ex vivo excitotoxic striatal lesion models
by: Amy McCaughey-Chapman, et al.
Published: (2022-09-01)