Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series
Objective To evaluate changes in retinal nerve fiber layer (RNFL) and macular thicknesses, included ganglion cell-inner plexiform layer (GCIPL) thickness, in patients with spontaneous intracranial hypotension (SIH). Methods This was a retrospective, nonrandom, observational case series study. Compre...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-10-01
|
| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605211050791 |
| _version_ | 1828146980362125312 |
|---|---|
| author | Li-Guo Feng Ying Chen Fei-Fang He Yu-Feng Yao |
| author_facet | Li-Guo Feng Ying Chen Fei-Fang He Yu-Feng Yao |
| author_sort | Li-Guo Feng |
| collection | DOAJ |
| description | Objective To evaluate changes in retinal nerve fiber layer (RNFL) and macular thicknesses, included ganglion cell-inner plexiform layer (GCIPL) thickness, in patients with spontaneous intracranial hypotension (SIH). Methods This was a retrospective, nonrandom, observational case series study. Comprehensive ophthalmic examinations and systemic examinations were performed. Spectral domain optical coherence tomography angiography scanning was used to measure peripapillary RNFL thickness and macular volume. Results In total, 108 eyes in 54 patients with SIH were evaluated; these were compared with 108 eyes in 54 healthy controls. The mean ages were 38.2 ± 9.4 years (patients with SIH) and 38.9 ± 9.4 years (healthy controls). In both groups, 33 patients were women (61.1%). The peripapillary RNFL and GCIPL were thinner in patients with SIH than in healthy controls (100.08 ± 9.94 µm vs 104.83 ± 8.35 µm and 81.46 ± 5.67 µm vs 85.67 ± 4.57 µm, respectively). Among patients with SIH, the GCIPL was thinner in patients with visual field defects (79.81 ± 5.62 µm vs 82.39 ± 5.12 µm). Conclusions The RNFL and GCIPL were thinner in patients with SIH than in healthy controls. The GCIPL was thinner in eyes with visual field defects among patients with SIH. |
| first_indexed | 2024-04-11T20:54:54Z |
| format | Article |
| id | doaj.art-9b1a9306034345869bc240a52df62fe2 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-04-11T20:54:54Z |
| publishDate | 2021-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-9b1a9306034345869bc240a52df62fe22022-12-22T04:03:44ZengSAGE PublishingJournal of International Medical Research1473-23002021-10-014910.1177/03000605211050791Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case seriesLi-Guo FengYing ChenFei-Fang HeYu-Feng YaoObjective To evaluate changes in retinal nerve fiber layer (RNFL) and macular thicknesses, included ganglion cell-inner plexiform layer (GCIPL) thickness, in patients with spontaneous intracranial hypotension (SIH). Methods This was a retrospective, nonrandom, observational case series study. Comprehensive ophthalmic examinations and systemic examinations were performed. Spectral domain optical coherence tomography angiography scanning was used to measure peripapillary RNFL thickness and macular volume. Results In total, 108 eyes in 54 patients with SIH were evaluated; these were compared with 108 eyes in 54 healthy controls. The mean ages were 38.2 ± 9.4 years (patients with SIH) and 38.9 ± 9.4 years (healthy controls). In both groups, 33 patients were women (61.1%). The peripapillary RNFL and GCIPL were thinner in patients with SIH than in healthy controls (100.08 ± 9.94 µm vs 104.83 ± 8.35 µm and 81.46 ± 5.67 µm vs 85.67 ± 4.57 µm, respectively). Among patients with SIH, the GCIPL was thinner in patients with visual field defects (79.81 ± 5.62 µm vs 82.39 ± 5.12 µm). Conclusions The RNFL and GCIPL were thinner in patients with SIH than in healthy controls. The GCIPL was thinner in eyes with visual field defects among patients with SIH.https://doi.org/10.1177/03000605211050791 |
| spellingShingle | Li-Guo Feng Ying Chen Fei-Fang He Yu-Feng Yao Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series Journal of International Medical Research |
| title | Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series |
| title_full | Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series |
| title_fullStr | Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series |
| title_full_unstemmed | Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series |
| title_short | Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series |
| title_sort | retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension a retrospective case series |
| url | https://doi.org/10.1177/03000605211050791 |
| work_keys_str_mv | AT liguofeng retinalnervefiberlayercharacteristicsinpatientswithspontaneousintracranialhypotensionaretrospectivecaseseries AT yingchen retinalnervefiberlayercharacteristicsinpatientswithspontaneousintracranialhypotensionaretrospectivecaseseries AT feifanghe retinalnervefiberlayercharacteristicsinpatientswithspontaneousintracranialhypotensionaretrospectivecaseseries AT yufengyao retinalnervefiberlayercharacteristicsinpatientswithspontaneousintracranialhypotensionaretrospectivecaseseries |