ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.

ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.

Oxidative stress in the central nervous system mediates the increase in sympathetic tone that precedes the development of hypertension. We hypothesized that by transforming Angiotensin-II (AngII) into Ang-(1-7), ACE2 might reduce AngII-mediated oxidative stress in the brain and prevent autonomic dys...

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Bibliographic Details
Main Authors: Huijing Xia, Sonia Suda, Sharell Bindom, Yumei Feng, Susan B Gurley, Dale Seth, L Gabriel Navar, Eric Lazartigues
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21818366/pdf/?tool=EBI

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