NKT cells: characteristic features and functional significance in the immune response regulation
A lymphocyte lineage which is referred to as NKT cells expresses both markers of NK cells and T lymphocytes. NKT cells play a key role in the regulation of different types of immune responses, contribute to the protection from tumor growth and metastasis, from different intracellular infections and...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2022-11-01
|
| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/767 |
| _version_ | 1826557104841818112 |
|---|---|
| author | O. V. Akinfieva L. N. Bubnova S. S. Bessmeltsev |
| author_facet | O. V. Akinfieva L. N. Bubnova S. S. Bessmeltsev |
| author_sort | O. V. Akinfieva |
| collection | DOAJ |
| description | A lymphocyte lineage which is referred to as NKT cells expresses both markers of NK cells and T lymphocytes. NKT cells play a key role in the regulation of different types of immune responses, contribute to the protection from tumor growth and metastasis, from different intracellular infections and from development of autoimmune diseases. NKT cells are of vital importance in the induction of antitumoral immune response due to their production of IFN-γ which activates NK cells, CD8+ T lymphocytes and macrophages. |
| first_indexed | 2024-04-09T20:23:18Z |
| format | Article |
| id | doaj.art-9b1d3d4b85b64275b26dadac8cf7d693 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2025-03-14T08:23:18Z |
| publishDate | 2022-11-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-9b1d3d4b85b64275b26dadac8cf7d6932025-03-02T13:07:16ZrusABV-pressОнкогематология1818-83462413-40232022-11-01043947645NKT cells: characteristic features and functional significance in the immune response regulationO. V. Akinfieva0L. N. Bubnova1S. S. Bessmeltsev2Russian Research Institute of Hematology and TransfusiologyRussian Research Institute of Hematology and TransfusiologyRussian Research Institute of Hematology and TransfusiologyA lymphocyte lineage which is referred to as NKT cells expresses both markers of NK cells and T lymphocytes. NKT cells play a key role in the regulation of different types of immune responses, contribute to the protection from tumor growth and metastasis, from different intracellular infections and from development of autoimmune diseases. NKT cells are of vital importance in the induction of antitumoral immune response due to their production of IFN-γ which activates NK cells, CD8+ T lymphocytes and macrophages.https://oncohematology.abvpress.ru/ongm/article/view/767ifn-γnkt cellsnk cellsautoimmune diseasesantitumoral immune response |
| spellingShingle | O. V. Akinfieva L. N. Bubnova S. S. Bessmeltsev NKT cells: characteristic features and functional significance in the immune response regulation Онкогематология ifn-γ nkt cells nk cells autoimmune diseases antitumoral immune response |
| title | NKT cells: characteristic features and functional significance in the immune response regulation |
| title_full | NKT cells: characteristic features and functional significance in the immune response regulation |
| title_fullStr | NKT cells: characteristic features and functional significance in the immune response regulation |
| title_full_unstemmed | NKT cells: characteristic features and functional significance in the immune response regulation |
| title_short | NKT cells: characteristic features and functional significance in the immune response regulation |
| title_sort | nkt cells characteristic features and functional significance in the immune response regulation |
| topic | ifn-γ nkt cells nk cells autoimmune diseases antitumoral immune response |
| url | https://oncohematology.abvpress.ru/ongm/article/view/767 |
| work_keys_str_mv | AT ovakinfieva nktcellscharacteristicfeaturesandfunctionalsignificanceintheimmuneresponseregulation AT lnbubnova nktcellscharacteristicfeaturesandfunctionalsignificanceintheimmuneresponseregulation AT ssbessmeltsev nktcellscharacteristicfeaturesandfunctionalsignificanceintheimmuneresponseregulation |