Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region

The Kaluga region is an area with high risk for multiple sclerosis(MS). We demonstrated the prognostic role of type of a MSdebut and duration of the first remission for the clinical course ofthe disease. There was no association between the mean annualrelapse rate and mean annual rate of MS progress...

Full description

Bibliographic Details
Main Authors: N. N. Maslova, E. A. Andreeva, Yu. A. Belyy, E. V. Yerokhina
Format: Article
Language:English
Published: Research Center of Neurology 2017-02-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/174/6
Description
Summary:The Kaluga region is an area with high risk for multiple sclerosis(MS). We demonstrated the prognostic role of type of a MSdebut and duration of the first remission for the clinical course ofthe disease. There was no association between the mean annualrelapse rate and mean annual rate of MS progression. In patientswith various MS variants were found decreased retinal nervefibers layer thickness in all sectors, most prominent in the temporalsector, and the reduction of macular volume. We showedthe role of optical coherent tomography and the visual evokedpotentials for early diagnostics of multiple sclerosis and for monitoringof demyelination and neurodegeneration of optic nerveand in CNS in general.
ISSN:2075-5473
2409-2533