Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region

The Kaluga region is an area with high risk for multiple sclerosis(MS). We demonstrated the prognostic role of type of a MSdebut and duration of the first remission for the clinical course ofthe disease. There was no association between the mean annualrelapse rate and mean annual rate of MS progress...

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Main Authors: N. N. Maslova, E. A. Andreeva, Yu. A. Belyy, E. V. Yerokhina
Format: Article
Language:English
Published: Research Center of Neurology 2017-02-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/174/6
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author N. N. Maslova
E. A. Andreeva
Yu. A. Belyy
E. V. Yerokhina
author_facet N. N. Maslova
E. A. Andreeva
Yu. A. Belyy
E. V. Yerokhina
author_sort N. N. Maslova
collection DOAJ
description The Kaluga region is an area with high risk for multiple sclerosis(MS). We demonstrated the prognostic role of type of a MSdebut and duration of the first remission for the clinical course ofthe disease. There was no association between the mean annualrelapse rate and mean annual rate of MS progression. In patientswith various MS variants were found decreased retinal nervefibers layer thickness in all sectors, most prominent in the temporalsector, and the reduction of macular volume. We showedthe role of optical coherent tomography and the visual evokedpotentials for early diagnostics of multiple sclerosis and for monitoringof demyelination and neurodegeneration of optic nerveand in CNS in general.
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spelling doaj.art-9b223b234b614bf591f795121d9686ea2022-12-22T03:29:33ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-0183303710.17816/psaic17479Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga regionN. N. Maslova0E. A. Andreeva1Yu. A. Belyy2E. V. Yerokhina3Research Centre «Eye microsurgery name of academician S.N. Fedorov» (Kaluga)Research Centre «Eye microsurgery name of academician S.N. Fedorov» (Kaluga)Research Centre «Eye microsurgery name of academician S.N. Fedorov» (Kaluga)Research Centre «Eye microsurgery name of academician S.N. Fedorov» (Kaluga)The Kaluga region is an area with high risk for multiple sclerosis(MS). We demonstrated the prognostic role of type of a MSdebut and duration of the first remission for the clinical course ofthe disease. There was no association between the mean annualrelapse rate and mean annual rate of MS progression. In patientswith various MS variants were found decreased retinal nervefibers layer thickness in all sectors, most prominent in the temporalsector, and the reduction of macular volume. We showedthe role of optical coherent tomography and the visual evokedpotentials for early diagnostics of multiple sclerosis and for monitoringof demyelination and neurodegeneration of optic nerveand in CNS in general.https://annaly-nevrologii.com/journal/pathID/article/viewFile/174/6multiple sclerosisoptical neuritisoptical coherent tomographythe visual caused potentials
spellingShingle N. N. Maslova
E. A. Andreeva
Yu. A. Belyy
E. V. Yerokhina
Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region
Анналы клинической и экспериментальной неврологии
multiple sclerosis
optical neuritis
optical coherent tomography
the visual caused potentials
title Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region
title_full Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region
title_fullStr Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region
title_full_unstemmed Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region
title_short Clinical, epidemiological and neuro-ophthalmological features of patients with multiple sclerosis: study of Kaluga region
title_sort clinical epidemiological and neuro ophthalmological features of patients with multiple sclerosis study of kaluga region
topic multiple sclerosis
optical neuritis
optical coherent tomography
the visual caused potentials
url https://annaly-nevrologii.com/journal/pathID/article/viewFile/174/6
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AT yuabelyy clinicalepidemiologicalandneuroophthalmologicalfeaturesofpatientswithmultiplesclerosisstudyofkalugaregion
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