A Dutch highly pathogenic H5N6 avian influenza virus showed remarkable tropism for extra-respiratory organs and caused severe disease but was not transmissible via air in the ferret model

A Dutch highly pathogenic H5N6 avian influenza virus showed remarkable tropism for extra-respiratory organs and caused severe disease but was not transmissible via air in the ferret model

ABSTRACT Continued circulation of A/H5N1 influenza viruses of the A/goose/Guangdong/1/96 lineage in poultry has resulted in the diversification in multiple genetic and antigenic clades. Since 2009, clade 2.3.4.4 hemagglutinin (HA) containing viruses harboring the internal and neuraminidase (NA) gene...

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Bibliographic Details
Main Authors: Sander Herfst, Lineke Begeman, Monique I. Spronken, Marjolein J. Poen, Dirk Eggink, Dennis de Meulder, Pascal Lexmond, Theo M. Bestebroer, Marion P. G. Koopmans, Thijs Kuiken, Mathilde Richard, Ron A. M. Fouchier
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
influenza
HPAI
H5N6
transmission
risk assessment
ferret
Online Access:https://journals.asm.org/doi/10.1128/msphere.00200-23

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