Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

Macrophage infiltration of white adipose tissue (WAT) is implicated in the metabolic complications of obesity. The precipitating event(s) and function(s) of macrophage infiltration into WAT are unknown. We demonstrate that >90% of all macrophages in WAT of obese mice and humans are localized to d...

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Bibliographic Details
Main Authors: Saverio Cinti, Grant Mitchell, Giorgio Barbatelli, Incoronata Murano, Enzo Ceresi, Emanuela Faloia, Shupei Wang, Melanie Fortier, Andrew S. Greenberg, Martin S. Obin
Format: Article
Language:English
Published: Elsevier 2005-11-01
Series:Journal of Lipid Research
Subjects:
obesity
inflammation
apoptosis
necrosis
adipocyte hypertrophy
multinucleate giant cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328728

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http://www.sciencedirect.com/science/article/pii/S0022227520328728

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