Puzzling mRNA: Alternative splicing fine-tunes specificity and function

In this issue of the Biomedical Journal we discover how alternative splicing might modulate the cell-type specificity and exact function of a ubiquitous purinergic receptor and how the beta blocker propanolol can contribute to breast cancer therapy. Moreover, we learn which culture conditions genera...

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Main Author: Sophia Julia Häfner
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417019304676
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author Sophia Julia Häfner
author_facet Sophia Julia Häfner
author_sort Sophia Julia Häfner
collection DOAJ
description In this issue of the Biomedical Journal we discover how alternative splicing might modulate the cell-type specificity and exact function of a ubiquitous purinergic receptor and how the beta blocker propanolol can contribute to breast cancer therapy. Moreover, we learn which culture conditions generate the best vascularisation of tissue engineered bone and which are the clinical features of acute necrotising encephalopathy in adults. Other studies reveal, how laser irradiation can fix fractured all-ceramic dental restorations in situ, and finally that nuclear magnetic resonance holds great potential for the rapid detection of pathogens. Keywords: Alternative splicing, P2RX7receptor, Propanolol, Tissue engineering, Acute necrotizing encephalopathy
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spelling doaj.art-9b297ada921c4cfe8b498fa0a2a1faf22022-12-22T04:03:36ZengElsevierBiomedical Journal2319-41702019-06-01423137140Puzzling mRNA: Alternative splicing fine-tunes specificity and functionSophia Julia Häfner0University of Copenhagen, BRIC Biotech Research & Innovation Centre, Anders Lund Group, Ole Maaløes Vej 5, 2200, Copenhagen, DenmarkIn this issue of the Biomedical Journal we discover how alternative splicing might modulate the cell-type specificity and exact function of a ubiquitous purinergic receptor and how the beta blocker propanolol can contribute to breast cancer therapy. Moreover, we learn which culture conditions generate the best vascularisation of tissue engineered bone and which are the clinical features of acute necrotising encephalopathy in adults. Other studies reveal, how laser irradiation can fix fractured all-ceramic dental restorations in situ, and finally that nuclear magnetic resonance holds great potential for the rapid detection of pathogens. Keywords: Alternative splicing, P2RX7receptor, Propanolol, Tissue engineering, Acute necrotizing encephalopathyhttp://www.sciencedirect.com/science/article/pii/S2319417019304676
spellingShingle Sophia Julia Häfner
Puzzling mRNA: Alternative splicing fine-tunes specificity and function
Biomedical Journal
title Puzzling mRNA: Alternative splicing fine-tunes specificity and function
title_full Puzzling mRNA: Alternative splicing fine-tunes specificity and function
title_fullStr Puzzling mRNA: Alternative splicing fine-tunes specificity and function
title_full_unstemmed Puzzling mRNA: Alternative splicing fine-tunes specificity and function
title_short Puzzling mRNA: Alternative splicing fine-tunes specificity and function
title_sort puzzling mrna alternative splicing fine tunes specificity and function
url http://www.sciencedirect.com/science/article/pii/S2319417019304676
work_keys_str_mv AT sophiajuliahafner puzzlingmrnaalternativesplicingfinetunesspecificityandfunction