Antiproliferative Copper(II) Complexes Bearing Mixed Chelating Ligands: Structural Characterization, ROS Scavenging, In Silico Studies, and Anti-Melanoma Activity

Antiproliferative Copper(II) Complexes Bearing Mixed Chelating Ligands: Structural Characterization, ROS Scavenging, In Silico Studies, and Anti-Melanoma Activity

Melanoma is a skin cancer characterized by rapid growth and spread for which current therapies produce both resistance and increased risk of infection. To develop new anti-melanoma biocompatible species, the series of complexes Cu(N-N)(bzac)(X)⋅nH<sub>2</sub>O (N-N: 1,10-phenanthroline/2...

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Bibliographic Details
Main Authors: Rodica Olar, Catalin Maxim, Mihaela Badea, Mihaela Bacalum, Mina Raileanu, Speranta Avram, Nataša Čelan Korošin, Teodora Burlanescu, Arpad Mihai Rostas
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
Cu(II) complex
structure
ROS
cytotoxicity
melanoma cells
bioinformatics
Online Access:https://www.mdpi.com/1999-4923/14/8/1692

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