HPV-associated cervicitis

Cervical inflammatory disease associated with papillomavirus infection is one of the most common inflammatory diseases of the pelvic organs and plays a role in developing cervical dysplasia and cancer. Over the past 15 years, Russia has seen an increase in the proportion of neglected cervical cancer...

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Main Authors: Margarita V. Andreeva, Kristina I. Zakharova
Format: Article
Language:Russian
Published: IP Berlin A.V. 2023-01-01
Series:Гинекология
Subjects:
Online Access:https://gynecology.orscience.ru/2079-5831/article/viewFile/106984/pdf
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author Margarita V. Andreeva
Kristina I. Zakharova
author_facet Margarita V. Andreeva
Kristina I. Zakharova
author_sort Margarita V. Andreeva
collection DOAJ
description Cervical inflammatory disease associated with papillomavirus infection is one of the most common inflammatory diseases of the pelvic organs and plays a role in developing cervical dysplasia and cancer. Over the past 15 years, Russia has seen an increase in the proportion of neglected cervical cancer cases. Currently, the management and treatment strategy for cervicitis associated with human papillomavirus (HPV) and cervical intraepithelial dysplasia ranges from monitoring with HPV testing and cytological control to excision and cervical conization. The immune status determines the course of the papillomavirus infection, which may be transient, latent, or persistent. In most cases (7080%), HPV is eliminated spontaneously. The detection of HPV DNA with clinical and morphological changes indicates a latent course of the disease. The complex use of clinical data and morphological and molecular biological studies results is most promising in identifying early prognostic markers of cervical malignancy. It is the basis for further search for cervical precancer progression pathogenetic markers.
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spelling doaj.art-9b2c981e24954b9d9a59330fba7394ec2023-01-23T16:49:07ZrusIP Berlin A.V.Гинекология2079-56962079-58312023-01-0124653954210.26442/20795696.2022.6.20195779474HPV-associated cervicitisMargarita V. Andreeva0https://orcid.org/0000-0002-2111-0351Kristina I. Zakharova1https://orcid.org/0000-0002-7952-8961Volgograd State Medical UniversityVolgograd State Medical UniversityCervical inflammatory disease associated with papillomavirus infection is one of the most common inflammatory diseases of the pelvic organs and plays a role in developing cervical dysplasia and cancer. Over the past 15 years, Russia has seen an increase in the proportion of neglected cervical cancer cases. Currently, the management and treatment strategy for cervicitis associated with human papillomavirus (HPV) and cervical intraepithelial dysplasia ranges from monitoring with HPV testing and cytological control to excision and cervical conization. The immune status determines the course of the papillomavirus infection, which may be transient, latent, or persistent. In most cases (7080%), HPV is eliminated spontaneously. The detection of HPV DNA with clinical and morphological changes indicates a latent course of the disease. The complex use of clinical data and morphological and molecular biological studies results is most promising in identifying early prognostic markers of cervical malignancy. It is the basis for further search for cervical precancer progression pathogenetic markers.https://gynecology.orscience.ru/2079-5831/article/viewFile/106984/pdfcervicitiscervical intraepithelial neoplasiahuman papilloma viruscervical cancer
spellingShingle Margarita V. Andreeva
Kristina I. Zakharova
HPV-associated cervicitis
Гинекология
cervicitis
cervical intraepithelial neoplasia
human papilloma virus
cervical cancer
title HPV-associated cervicitis
title_full HPV-associated cervicitis
title_fullStr HPV-associated cervicitis
title_full_unstemmed HPV-associated cervicitis
title_short HPV-associated cervicitis
title_sort hpv associated cervicitis
topic cervicitis
cervical intraepithelial neoplasia
human papilloma virus
cervical cancer
url https://gynecology.orscience.ru/2079-5831/article/viewFile/106984/pdf
work_keys_str_mv AT margaritavandreeva hpvassociatedcervicitis
AT kristinaizakharova hpvassociatedcervicitis