Assessment of Opioid-Induced Immunomodulation in Experimental and Clinical Sepsis
CONTEXT:. Opioids remain a standard supportive therapy in patients admitted to the ICU with sepsis. However, as preclinical models indicate an association between opioid exposure and immunosuppression, the use of this class of drugs warrants investigation. The objective of this study was to investig...
Main Authors: | Brittany D. Bissell, PharmD, PhD, FCCM, BCCCP, Jamie L. Sturgill, PhD, Maria E. C. Bruno, PhD, Erick D. Lewis, MS, Marlene E. Starr, PhD |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2023-01-01
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Series: | Critical Care Explorations |
Online Access: | http://journals.lww.com/10.1097/CCE.0000000000000849 |
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