Differences in the pathogenicity and inflammatory responses induced by avian influenza A/H7N9 virus infection in BALB/c and C57BL/6 mouse models.

Differences in the pathogenicity and inflammatory responses induced by avian influenza A/H7N9 virus infection in BALB/c and C57BL/6 mouse models.

Avian influenza A/H7N9 virus infection causes pneumonia in humans with a high case fatality rate. However, virus-induced modulation of immune responses is being recognized increasingly as a factor in the pathogenesis of this disease. In this study, we compared the pathogenicity of A/H7N9 infection i...

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Bibliographic Details
Main Authors: Guangyu Zhao, Chenfeng Liu, Zhihua Kou, Tongtong Gao, Ting Pan, Xiaohong Wu, Hong Yu, Yan Guo, Yang Zeng, Lanying Du, Shibo Jiang, Shihui Sun, Yusen Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3968029?pdf=render

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