Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2

Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2

Abstract A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a global pandemic of coronavirus disease 19. Coronaviruses, including SARS-CoV-2, use RNA-dependent RNA polymerase (RdRP) for viral replication and transcription. Since RdRP is a promising therapeu...

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Bibliographic Details
Main Authors: Mitsuhiro Machitani, Junko Takei, Mika K. Kaneko, Saori Ueki, Hirofumi Ohashi, Koichi Watashi, Yukinari Kato, Kenkichi Masutomi
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Virology Journal
Subjects:
SARS-CoV-2
RNA-dependent RNA polymerase
nsp12
Monoclonal antibody
Online Access:https://doi.org/10.1186/s12985-022-01948-2

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