The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

Nowadays, the selective introduction of fluorine into bioactive compounds is a mature strategy in the design of drugs allowing to increase efficiency, biological half-life and bio-absorption. On the other hand, amino acids (AAs) represent one of the most ubiquitious classes of naturally occurring or...

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Bibliographic Details
Main Authors: Qian Wang, Jianlin Han, Alexander Sorochinsky, Aitor Landa, Greg Butler, Vadim A. Soloshonok
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceuticals
Subjects:
pharmaceuticals
tailor-made amino acids
fluorine
drug design
asymmetric synthesis
Online Access:https://www.mdpi.com/1424-8247/15/8/999

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