Protecting the anaesthetised brain
The anaesthetized brain is vulnerable to ischaemic insults, which could result in neurological deficits ranging from neuropsychological disturbances to stroke and even death. The risk of perioperative brain injury is relatively high in cardiac, neurosurgical and major vascular surgery, although it h...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2014-04-01
|
| Series: | Journal of Neuroanaesthesiology and Critical Care |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/2348-0548.124841 |
| _version_ | 1818152448048496640 |
|---|---|
| author | Mary Abraham |
| author_facet | Mary Abraham |
| author_sort | Mary Abraham |
| collection | DOAJ |
| description | The anaesthetized brain is vulnerable to ischaemic insults, which could result in neurological deficits ranging from neuropsychological disturbances to stroke and even death. The risk of perioperative brain injury is relatively high in cardiac, neurosurgical and major vascular surgery, although it has also rarely been reported in noncardiac nonneurosurgical operations. Besides underlying risk factors such as cerebrovascular disease, advanced age, and cardiovascular disease, anaesthesia and surgery per se could also be a contributory factor. The anaesthesiologist plays a pivotal role in protecting the anaesthetized brain, both by taking preventive measures and instituting brain protection strategies. Despite advances and breakthroughs in pharmacological neuroprotection in the laboratory, currently there is no drug, anaesthetic or non-anaesthetic, which is available for clinical use. The anaesthesiologist has to rely on non-pharmacological modalities and neuromonitoring to prevent intraoperative brain injury |
| first_indexed | 2024-12-11T13:54:52Z |
| format | Article |
| id | doaj.art-9b3c49cc09cc476cb9e54df03603e13b |
| institution | Directory Open Access Journal |
| issn | 2348-0548 2348-926X |
| language | English |
| last_indexed | 2024-12-11T13:54:52Z |
| publishDate | 2014-04-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Neuroanaesthesiology and Critical Care |
| spelling | doaj.art-9b3c49cc09cc476cb9e54df03603e13b2022-12-22T01:04:06ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neuroanaesthesiology and Critical Care2348-05482348-926X2014-04-01010102003910.4103/2348-0548.124841Protecting the anaesthetised brainMary Abraham0Department of Anaesthesiology and Pain Medicine, Fortis Hospital, Noida, Uttar Pradesh, IndiaThe anaesthetized brain is vulnerable to ischaemic insults, which could result in neurological deficits ranging from neuropsychological disturbances to stroke and even death. The risk of perioperative brain injury is relatively high in cardiac, neurosurgical and major vascular surgery, although it has also rarely been reported in noncardiac nonneurosurgical operations. Besides underlying risk factors such as cerebrovascular disease, advanced age, and cardiovascular disease, anaesthesia and surgery per se could also be a contributory factor. The anaesthesiologist plays a pivotal role in protecting the anaesthetized brain, both by taking preventive measures and instituting brain protection strategies. Despite advances and breakthroughs in pharmacological neuroprotection in the laboratory, currently there is no drug, anaesthetic or non-anaesthetic, which is available for clinical use. The anaesthesiologist has to rely on non-pharmacological modalities and neuromonitoring to prevent intraoperative brain injuryhttp://www.thieme-connect.de/DOI/DOI?10.4103/2348-0548.124841cerebral ischaemiaintraoperativeneuroprotection |
| spellingShingle | Mary Abraham Protecting the anaesthetised brain Journal of Neuroanaesthesiology and Critical Care cerebral ischaemia intraoperative neuroprotection |
| title | Protecting the anaesthetised brain |
| title_full | Protecting the anaesthetised brain |
| title_fullStr | Protecting the anaesthetised brain |
| title_full_unstemmed | Protecting the anaesthetised brain |
| title_short | Protecting the anaesthetised brain |
| title_sort | protecting the anaesthetised brain |
| topic | cerebral ischaemia intraoperative neuroprotection |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/2348-0548.124841 |
| work_keys_str_mv | AT maryabraham protectingtheanaesthetisedbrain |