Enhanced docetaxel therapeutic effect using dual targeted SRL-2 and TA1 aptamer conjugated micelles in inhibition Balb/c mice breast cancer model

Enhanced docetaxel therapeutic effect using dual targeted SRL-2 and TA1 aptamer conjugated micelles in inhibition Balb/c mice breast cancer model

Abstract Effective targeting and delivery of large amounts of medications into the cancer cells enhance their therapeutic efficacy through saturation of cellular defensive mechanisms, which is the most privilege of nano drug delivery systems (NDDS) compared to traditional approaches. Herein, we desi...

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Bibliographic Details
Main Authors: Yasamin Davatgaran Taghipour, Amir Zarebkohan, Roya Salehi, Mehdi Talebi, Reza Rahbarghazi, Monireh Khordadmehr, Sharareh Khavandkari, Fahimeh Badparvar, Vladimir P. Torchilin
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Drug resistance
DTX
Delivery
Smart
GSH/pH responsive
TA1 aptamer
Online Access:https://doi.org/10.1038/s41598-024-75042-8

Internet

https://doi.org/10.1038/s41598-024-75042-8

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