Experience of Using Activated Protein C in a Patient With Emphysematous Pyelonephritis Receiving Percutaneous Nephrostomy Drainage

Drotrecogin alfa, a type of recombinant human activated protein C, has potential to reduce the mortality in severe sepsis, but may simultaneously increase the risk of serious bleeding events. Here, we report an 81-yearold female suffering from emphysematous pyelonephritis who recovered after appropr...

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Bibliographic Details
Main Authors: Yueh-Hung Lin, Shou-Chuan Shih, Chien-Liang Wu, Yi-Chou Chen, Yu-Wei Chen, Shih-Yi Lee
Format: Article
Language:English
Published: Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) 2010-09-01
Series:International Journal of Gerontology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1873959810700429
Description
Summary:Drotrecogin alfa, a type of recombinant human activated protein C, has potential to reduce the mortality in severe sepsis, but may simultaneously increase the risk of serious bleeding events. Here, we report an 81-yearold female suffering from emphysematous pyelonephritis who recovered after appropriate management, including antibiotics, percutaneous nephrostomy drainage and administration of activated protein C. This case showed that percutaneous nephrostomy drainage is not an absolute contraindication in the prescribing of activated protein C in patients with severe sepsis.
ISSN:1873-9598