Cardiac toxicity of fluoroquinolones and bedaquiline
The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented. The article demonstrates the importance of concomitan...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2019-05-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1264 |
| _version_ | 1797702852199579648 |
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| author | G. N. Mozhokinа A. G. Sаmoylovа |
| author_facet | G. N. Mozhokinа A. G. Sаmoylovа |
| author_sort | G. N. Mozhokinа |
| collection | DOAJ |
| description | The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented. The article demonstrates the importance of concomitant factors (potassium level in the blood, concurrent heart disorders, a genetically determined amount of HERG receptors in the myocardium, concomitant drug therapy) in the development of the cardiac toxicity caused by fluoroquinolones and bedaquiline. |
| first_indexed | 2024-03-12T04:55:59Z |
| format | Article |
| id | doaj.art-9b423f3cc03048e6bd52e5a4c3874258 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2024-03-12T04:55:59Z |
| publishDate | 2019-05-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-9b423f3cc03048e6bd52e5a4c38742582023-09-03T09:15:11ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-05-01974566210.21292/2075-1230-2019-97-4-56-621264Cardiac toxicity of fluoroquinolones and bedaquilineG. N. Mozhokinа0A. G. Sаmoylovа1ФГБУ Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеванийФГБУ Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеванийThe review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented. The article demonstrates the importance of concomitant factors (potassium level in the blood, concurrent heart disorders, a genetically determined amount of HERG receptors in the myocardium, concomitant drug therapy) in the development of the cardiac toxicity caused by fluoroquinolones and bedaquiline.https://www.tibl-journal.com/jour/article/view/1264кардиотоксичностьинтервал qtфторхинолоныбедаквилин |
| spellingShingle | G. N. Mozhokinа A. G. Sаmoylovа Cardiac toxicity of fluoroquinolones and bedaquiline Туберкулез и болезни лёгких кардиотоксичность интервал qt фторхинолоны бедаквилин |
| title | Cardiac toxicity of fluoroquinolones and bedaquiline |
| title_full | Cardiac toxicity of fluoroquinolones and bedaquiline |
| title_fullStr | Cardiac toxicity of fluoroquinolones and bedaquiline |
| title_full_unstemmed | Cardiac toxicity of fluoroquinolones and bedaquiline |
| title_short | Cardiac toxicity of fluoroquinolones and bedaquiline |
| title_sort | cardiac toxicity of fluoroquinolones and bedaquiline |
| topic | кардиотоксичность интервал qt фторхинолоны бедаквилин |
| url | https://www.tibl-journal.com/jour/article/view/1264 |
| work_keys_str_mv | AT gnmozhokina cardiactoxicityoffluoroquinolonesandbedaquiline AT agsamoylova cardiactoxicityoffluoroquinolonesandbedaquiline |