Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases

We report two cases of prenatally diagnosed cystic neuroblastoma (PDCN). In the first case, prenatal ultrasonography (US) at 33 weeks' gestation showed a 30 × 20 mm cyst at the upper pole of the right kidney. The size and content of the mass demonstrated no change during pregnancy. Postnatal US...

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Main Authors: Shinji Tanaka, Tatsuro Tajiri, Shin-ichi Noguchi, Keiko Ogita, Sachiyo Suita
Format: Article
Language:English
Published: Elsevier 2003-10-01
Series:Asian Journal of Surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S1015958409603092
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author Shinji Tanaka
Tatsuro Tajiri
Shin-ichi Noguchi
Keiko Ogita
Sachiyo Suita
author_facet Shinji Tanaka
Tatsuro Tajiri
Shin-ichi Noguchi
Keiko Ogita
Sachiyo Suita
author_sort Shinji Tanaka
collection DOAJ
description We report two cases of prenatally diagnosed cystic neuroblastoma (PDCN). In the first case, prenatal ultrasonography (US) at 33 weeks' gestation showed a 30 × 20 mm cyst at the upper pole of the right kidney. The size and content of the mass demonstrated no change during pregnancy. Postnatal US showed no change in the cystic mass 4 weeks after birth compared to the prenatal findings. The infant underwent total resection of the tumour at 28 days of age. In the second case, a left cystic mass measuring 50 × 40 mm was detected in a fetus in the 37th week of pregnancy. Postnatal US showed a cystic mass in the left adrenal gland. The US findings showed no change 18 days after birth and the infant underwent total resection of the tumour at 19 days of age. In both cases, pathological examination revealed a neuroblastoma and all of the biological prognostic factors were favourable. Surgical intervention was necessary for a final histological and biological diagnosis to be made. We recommend that prenatally suspected neuroblastomas should normally undergo surgical intervention, unless tumour size decreases within about 1 month after birth.
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spelling doaj.art-9b435fc1b67a468ab2bb7fe73c02ce6f2022-12-22T00:03:08ZengElsevierAsian Journal of Surgery1015-95842003-10-0126422522710.1016/S1015-9584(09)60309-2Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two CasesShinji TanakaTatsuro TajiriShin-ichi NoguchiKeiko OgitaSachiyo SuitaWe report two cases of prenatally diagnosed cystic neuroblastoma (PDCN). In the first case, prenatal ultrasonography (US) at 33 weeks' gestation showed a 30 × 20 mm cyst at the upper pole of the right kidney. The size and content of the mass demonstrated no change during pregnancy. Postnatal US showed no change in the cystic mass 4 weeks after birth compared to the prenatal findings. The infant underwent total resection of the tumour at 28 days of age. In the second case, a left cystic mass measuring 50 × 40 mm was detected in a fetus in the 37th week of pregnancy. Postnatal US showed a cystic mass in the left adrenal gland. The US findings showed no change 18 days after birth and the infant underwent total resection of the tumour at 19 days of age. In both cases, pathological examination revealed a neuroblastoma and all of the biological prognostic factors were favourable. Surgical intervention was necessary for a final histological and biological diagnosis to be made. We recommend that prenatally suspected neuroblastomas should normally undergo surgical intervention, unless tumour size decreases within about 1 month after birth.http://www.sciencedirect.com/science/article/pii/S1015958409603092
spellingShingle Shinji Tanaka
Tatsuro Tajiri
Shin-ichi Noguchi
Keiko Ogita
Sachiyo Suita
Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases
Asian Journal of Surgery
title Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases
title_full Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases
title_fullStr Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases
title_full_unstemmed Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases
title_short Prenatally Diagnosed Cystic Neuroblastoma: A Report of Two Cases
title_sort prenatally diagnosed cystic neuroblastoma a report of two cases
url http://www.sciencedirect.com/science/article/pii/S1015958409603092
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AT shinichinoguchi prenatallydiagnosedcysticneuroblastomaareportoftwocases
AT keikoogita prenatallydiagnosedcysticneuroblastomaareportoftwocases
AT sachiyosuita prenatallydiagnosedcysticneuroblastomaareportoftwocases