(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone
Matrix Metalloproteinases (MMPs) are a family of secreted and membrane-bound enzymes, of which 24 isoforms are known in humans. These enzymes degrade the proteins of the extracellular matrix and play a role of utmost importance in the physiological remodeling of all tissues. However, certain MMPs, s...
Main Authors: | , , , , , , |
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格式: | 文件 |
语言: | English |
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MDPI AG
2021-01-01
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丛编: | Pharmaceuticals |
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在线阅读: | https://www.mdpi.com/1424-8247/14/2/85 |