Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study.
The role of liver resection for non-colorectal, non-neuroendocrine, non-sarcoma (NCNNNS) metastases is ill-defined. This study aimed to examine the oncologic outcomes of liver resection in such patients.A retrospective analysis of liver resection for NCNNNS metastases was performed at two large cent...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4374793?pdf=render |
| _version_ | 1828396396665896960 |
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| author | Guillaume Martel Jeff Hawel Janelle Rekman Kristopher P Croome Kimberly Bertens Fady K Balaa Roberto Hernandez-Alejandro |
| author_facet | Guillaume Martel Jeff Hawel Janelle Rekman Kristopher P Croome Kimberly Bertens Fady K Balaa Roberto Hernandez-Alejandro |
| author_sort | Guillaume Martel |
| collection | DOAJ |
| description | The role of liver resection for non-colorectal, non-neuroendocrine, non-sarcoma (NCNNNS) metastases is ill-defined. This study aimed to examine the oncologic outcomes of liver resection in such patients.A retrospective analysis of liver resection for NCNNNS metastases was performed at two large centers. Liver resection was offered selectively in patients with stable disease. Oncologic outcomes were examined using the Kaplan-Meier method.Fifty-two patients underwent liver resection for NCNNNS metastases. Overall 5-year survival was 58%. Five-year survival was 85% for breast metastases, 66% for ocular melanoma, 83% for other melanomas, 50% for gastro-esophageal metastases, and 0% for renal cell carcinoma metastases. A contemporary colorectal liver metastasis cohort had a survival of 63% (p=0.89).Liver resection is an effective option in the management of selected patients with NCNNNS metastases which have been deemed stable. Five-year survival rates were comparable to that of a contemporary cohort of patients with colorectal liver metastases in carefully selected patients. Further, larger studies are required to help identify potential prognostic variables and aid in decision-making in this heterogeneous population. |
| first_indexed | 2024-12-10T08:29:21Z |
| format | Article |
| id | doaj.art-9b46584195304932a11bc1d36d154c43 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-10T08:29:21Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-9b46584195304932a11bc1d36d154c432022-12-22T01:56:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01103e012056910.1371/journal.pone.0120569Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study.Guillaume MartelJeff HawelJanelle RekmanKristopher P CroomeKimberly BertensFady K BalaaRoberto Hernandez-AlejandroThe role of liver resection for non-colorectal, non-neuroendocrine, non-sarcoma (NCNNNS) metastases is ill-defined. This study aimed to examine the oncologic outcomes of liver resection in such patients.A retrospective analysis of liver resection for NCNNNS metastases was performed at two large centers. Liver resection was offered selectively in patients with stable disease. Oncologic outcomes were examined using the Kaplan-Meier method.Fifty-two patients underwent liver resection for NCNNNS metastases. Overall 5-year survival was 58%. Five-year survival was 85% for breast metastases, 66% for ocular melanoma, 83% for other melanomas, 50% for gastro-esophageal metastases, and 0% for renal cell carcinoma metastases. A contemporary colorectal liver metastasis cohort had a survival of 63% (p=0.89).Liver resection is an effective option in the management of selected patients with NCNNNS metastases which have been deemed stable. Five-year survival rates were comparable to that of a contemporary cohort of patients with colorectal liver metastases in carefully selected patients. Further, larger studies are required to help identify potential prognostic variables and aid in decision-making in this heterogeneous population.http://europepmc.org/articles/PMC4374793?pdf=render |
| spellingShingle | Guillaume Martel Jeff Hawel Janelle Rekman Kristopher P Croome Kimberly Bertens Fady K Balaa Roberto Hernandez-Alejandro Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. PLoS ONE |
| title | Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. |
| title_full | Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. |
| title_fullStr | Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. |
| title_full_unstemmed | Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. |
| title_short | Liver resection for non-colorectal, non-carcinoid, non-sarcoma metastases: a multicenter study. |
| title_sort | liver resection for non colorectal non carcinoid non sarcoma metastases a multicenter study |
| url | http://europepmc.org/articles/PMC4374793?pdf=render |
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