Association of β-Globin Gene Haplotypes with Haematological Parameters and Foetal Haemoglobin among Patients with Sickle Cell Disorder in Raipur, Chhattisgarh, India

Association of β-Globin Gene Haplotypes with Haematological Parameters and Foetal Haemoglobin among Patients with Sickle Cell Disorder in Raipur, Chhattisgarh, India

Introduction: Sickle cell disease is caused by a single nucleotide substitution in the β-globin gene. The variations in Foetal Haemoglobin (HbF) levels, β-globin gene cluster haplotype have been used as predictors of disease severity in sickle cell disease patients. Aim: To determine the frequency...

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Bibliographic Details
Main Authors:	Sanjana Bhagat, Amar Singh Thakur
Format:	Article
Language:	English
Published:	JCDR Research and Publications Private Limited 2023-02-01
Series:	Journal of Clinical and Diagnostic Research
Subjects:	chromatography disease severity restriction fragment length analysis sickle cell traits
Online Access:	https://jcdr.net/articles/PDF/17445/58342_CE[Ra1]_F(KM)_PF1(JY_SS)_PFA(OM)_PB(JY_SS)_PN(SS).pdf

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