Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity

Objective. To study association between bone mineral density (BMD) and clinical and laboratory indices of rheumatoid arthritis (RA) activity Material and methods. 60 women with RA who had not received glucocorticoid and anti-osteoporotic therapy were included. 30 had unchanged menstrual cycle and 30...

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Main Authors: D. A. Gukasyan, R M Balabanova, A V Smirnov, E. L. Nassonov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2005-02-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/688
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author D. A. Gukasyan
R M Balabanova
A V Smirnov
E. L. Nassonov
author_facet D. A. Gukasyan
R M Balabanova
A V Smirnov
E. L. Nassonov
author_sort D. A. Gukasyan
collection DOAJ
description Objective. To study association between bone mineral density (BMD) and clinical and laboratory indices of rheumatoid arthritis (RA) activity Material and methods. 60 women with RA who had not received glucocorticoid and anti-osteoporotic therapy were included. 30 had unchanged menstrual cycle and 30 were postmenopausal. Lumbar spine BMD and proximal femur was studied with double radiological absorptiometry (QDR 1000 Hologic apparatus). W.Wilke indices were used to characterize activity and severity of RA. CRP level was evaluated with quantitative immunoenzyme method. Results. Significant negative association was revealed between spine and femoral neck BMD and RA severity so as between femoral neck BMD and CRP level in pts with unchanged menstrual cycle and in postmenopausal pts.
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spelling doaj.art-9b4cfeff29e94dac85a81267ef7acaf92023-03-22T13:45:40ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922005-02-01431182110.14412/1995-4484-2005-550628Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activityD. A. GukasyanR M BalabanovaA V SmirnovE. L. NassonovObjective. To study association between bone mineral density (BMD) and clinical and laboratory indices of rheumatoid arthritis (RA) activity Material and methods. 60 women with RA who had not received glucocorticoid and anti-osteoporotic therapy were included. 30 had unchanged menstrual cycle and 30 were postmenopausal. Lumbar spine BMD and proximal femur was studied with double radiological absorptiometry (QDR 1000 Hologic apparatus). W.Wilke indices were used to characterize activity and severity of RA. CRP level was evaluated with quantitative immunoenzyme method. Results. Significant negative association was revealed between spine and femoral neck BMD and RA severity so as between femoral neck BMD and CRP level in pts with unchanged menstrual cycle and in postmenopausal pts.https://rsp.mediar-press.net/rsp/article/view/688rheumatoid arthritisbone mineral densityosteoporosisactivityseverityseverity indexc- reactive protein
spellingShingle D. A. Gukasyan
R M Balabanova
A V Smirnov
E. L. Nassonov
Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
Научно-практическая ревматология
rheumatoid arthritis
bone mineral density
osteoporosis
activity
severity
severity index
c- reactive protein
title Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
title_full Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
title_fullStr Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
title_full_unstemmed Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
title_short Study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
title_sort study of correlation between bone mineral density and clinical and laboratory indices of rheumatoid arthritis activity
topic rheumatoid arthritis
bone mineral density
osteoporosis
activity
severity
severity index
c- reactive protein
url https://rsp.mediar-press.net/rsp/article/view/688
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AT rmbalabanova studyofcorrelationbetweenbonemineraldensityandclinicalandlaboratoryindicesofrheumatoidarthritisactivity
AT avsmirnov studyofcorrelationbetweenbonemineraldensityandclinicalandlaboratoryindicesofrheumatoidarthritisactivity
AT elnassonov studyofcorrelationbetweenbonemineraldensityandclinicalandlaboratoryindicesofrheumatoidarthritisactivity